We theoretically investigate the methodology involved in the minimization of the threshold of a Ge-on-Si laser and maximization of the slope efficiency in the presence of both biaxial tensile strain and n-type doping. Our findings suggest that there exist ultimate limits beyond which no further benefit can be realized through increased tensile strain or n-type doping. In this study, we quantify these limits, showing that the optimal design for minimizing threshold involves approximately 3.7% biaxial tensile strain and 2 x 10(18)cm(-3) n-type doping, whereas the optimal design for maximum slope efficiency involves approximately 2.3% biaxial tensile strain with 1 x 10(19)cm(-3) n-type doping. Increasing the strain and doping beyond these limits will degrade the threshold and slope efficiency, respectively. (C) 2016 The Japan Society of Applied Physics