DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Lee, Daeyoup | - |
dc.contributor.advisor | 이대엽 | - |
dc.contributor.author | Oh, Seung-Jun | - |
dc.date.accessioned | 2023-06-23T19:31:20Z | - |
dc.date.available | 2023-06-23T19:31:20Z | - |
dc.date.issued | 2022 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=997558&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/308817 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 생명과학과, 2022.2,[iv, 43 p. :] | - |
dc.description.abstract | Gene expression can be regulated by chromatin remodelers through nucleosome disassembly or rearrangement in promoter proximal regions or gene bodies. However, its mechanism is not well known. Here, I focused on Fft3 chromatin remodeler in Schizosaccharomyces pombe. By using Precision Nuclear Run-on sequencing (PRO-seq) that can detect active polymerase II with high resolution, I demonstrated that Fft3 was crucial in maintaining stable promoter proximal pausing, and without Fft3, premature transcription termination seemed to occur. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.title | Mechanistic study of Fun30 on transcription elongation in $\textit{S.pombe}$ | - |
dc.title.alternative | $\textit{S.pombe}$에서 Fun30가 전사 신장을 촉진하는 기작에 대한 연구 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :생명과학과, | - |
dc.contributor.alternativeauthor | 오승준 | - |
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