Extracellular matrix production of mesenchymal stem cells on nano-engineered decellularized matrix나노 구조 기반의 탈세포화 기질에 의한 중간엽줄기세포의 세포외기질 분비에 관한 연구
Mesenchymal stem cells (MSCs) are multipotent adult stem cells with high potential for stem cell therapies. Additional to the differentiation capacity of MSCs, extracellular matrix (ECM) remodeling property of MSCs plays important role in successful stem cell therapies. MSCs adapt and respond to the changes in the extracellular matrix (ECM) and remodel the ECM in their favor. Yet, very little attention was given to the ECM production and its effect on MSCs. To understand the ECM remodeling property of MSCs, in vivo mimicking nano-engineered decellularized-matrix was produced. Increased of ECM production on nanopattern and alteration of ECM related gene expressions were observed.
- Advisors
- Kim, Pilnamresearcher; 김필남researcher
- Description
- 한국과학기술원 :바이오및뇌공학과,
- Publisher
- 한국과학기술원
- Issue Date
- 2017
- Identifier
- 325007
- Language
- eng
- Description
학위논문(석사) - 한국과학기술원 : 바이오및뇌공학과, 2017.8,[iii, 35 p. :]
- Keywords
Mesenchymal stem cells▼ananopattern▼adecellularization▼aextracellular matrix▼aECM production; 중간엽줄기세포▼a나노구조▼a탈세포▼a세포외기질▼a세포외기질 분비
- Appears in Collection
- BiS-Theses_Master(석사논문)
- Files in This Item
- There are no files associated with this item.
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