MUTANT MICROORGANISMS HAVING HIGH ABILITY TO PRODUCE PUTRESCINE AND METHOD FOR PRODUCING PUTRESCINE USING THE SAME

Abstract

A mutant microorganism having the ability to produce putrescine and a method of preparing the microorganism in which at least one gene involved in the putrescine degradation or utilization pathway, selected from the group consisting of speE, speG, argl and puuP gene is inactivated or deleted and at least one gene selected from the group consisting of a puuA gene encoding .gamma.-glutamylputrescine synthase, a ygjG gene encoding putrescine transaminase and an argF gene encoding ornithine carbamoyltransferase chain F-monomer is further inactivated or deleted. The mutant microorganism and method providing a renewable biomass-derived source of produced putrescine as an alternative to the current chemical production processes available.