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Preference for Distinct Functional Conformations of the Dopamine Transporter Alters the Relationship between Subjective Effects of Cocaine and Stimulation of Mesolimbic Dopamine

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dc.contributor.authorKohut, Stephen J.ko
dc.contributor.authorHiranita, Takatoko
dc.contributor.authorHong, Soo-Kyungko
dc.contributor.authorEbbs, Aaron L.ko
dc.contributor.authorTronci, Valeriako
dc.contributor.authorGreen, Jenniferko
dc.contributor.authorGarces-Ramirez, Lindako
dc.contributor.authorChun, Lauren E.ko
dc.contributor.authorMereu, Maddalenako
dc.contributor.authorNewman, Amy H.ko
dc.contributor.authorKatz, Jonathan L.ko
dc.contributor.authorTanda, Gianluigiko
dc.date.accessioned2015-01-29T07:00:07Z-
dc.date.available2015-01-29T07:00:07Z-
dc.date.created2014-12-19-
dc.date.created2014-12-19-
dc.date.issued2014-11-
dc.identifier.citationBIOLOGICAL PSYCHIATRY, v.76, no.10, pp.802 - 809-
dc.identifier.issn0006-3223-
dc.identifier.urihttp://hdl.handle.net/10203/193809-
dc.description.abstractBackground: Subjective effects of cocaine are mediated primarily by dopamine (DA) transporter (DAT) blockade. The present study assessed the hypothesis that different DAT conformational equilibria regulate differences in cocaine-like subjective effects and extracellular DA induced by diverse DA-uptake inhibitors (DUIs).-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE INC-
dc.subjectUPTAKE INHIBITORS-
dc.subjectBENZTROPINE ANALOGS-
dc.subjectEXTRACELLULAR DOPAMINE-
dc.subjectPREFRONTAL CORTEX-
dc.subjectNUCLEUS-ACCUMBENS-
dc.subjectSQUIRREL-MONKEYS-
dc.subjectMONOAMINE UPTAKE-
dc.subjectABUSE LIABILITY-
dc.subjectBINDING-
dc.subjectMICRODIALYSIS-
dc.titlePreference for Distinct Functional Conformations of the Dopamine Transporter Alters the Relationship between Subjective Effects of Cocaine and Stimulation of Mesolimbic Dopamine-
dc.typeArticle-
dc.identifier.wosid000344733100008-
dc.identifier.scopusid2-s2.0-84927913557-
dc.type.rimsART-
dc.citation.volume76-
dc.citation.issue10-
dc.citation.beginningpage802-
dc.citation.endingpage809-
dc.citation.publicationnameBIOLOGICAL PSYCHIATRY-
dc.identifier.doi10.1016/j.biopsych.2014.03.031-
dc.contributor.nonIdAuthorKohut, Stephen J.-
dc.contributor.nonIdAuthorHiranita, Takato-
dc.contributor.nonIdAuthorEbbs, Aaron L.-
dc.contributor.nonIdAuthorTronci, Valeria-
dc.contributor.nonIdAuthorGreen, Jennifer-
dc.contributor.nonIdAuthorGarces-Ramirez, Linda-
dc.contributor.nonIdAuthorChun, Lauren E.-
dc.contributor.nonIdAuthorMereu, Maddalena-
dc.contributor.nonIdAuthorNewman, Amy H.-
dc.contributor.nonIdAuthorKatz, Jonathan L.-
dc.contributor.nonIdAuthorTanda, Gianluigi-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorADHD-
dc.subject.keywordAuthorbenztropine analogs-
dc.subject.keywordAuthorcocaine discrimination-
dc.subject.keywordAuthordopamine microdialysis-
dc.subject.keywordAuthordrug abuse and addiction-
dc.subject.keywordAuthornucleus accumbens shell-
dc.subject.keywordPlusUPTAKE INHIBITORS-
dc.subject.keywordPlusBENZTROPINE ANALOGS-
dc.subject.keywordPlusEXTRACELLULAR DOPAMINE-
dc.subject.keywordPlusPREFRONTAL CORTEX-
dc.subject.keywordPlusNUCLEUS-ACCUMBENS-
dc.subject.keywordPlusSQUIRREL-MONKEYS-
dc.subject.keywordPlusMONOAMINE UPTAKE-
dc.subject.keywordPlusABUSE LIABILITY-
dc.subject.keywordPlusBINDING-
dc.subject.keywordPlusMICRODIALYSIS-
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