Browse by Subject A-BETA
Showing results 1 to 45 of 45
| A rationally designed small molecule for identifying an in vivo link between metal-amyloid-beta complexes and the pathogenesis of Alzheimer's disease Beck, Michael W.; Oh, Shin Bi; Kerr, Richard A.; Lee, Hyuck Jin; Kim, So Hee; Kim, Sujeong; Jang, Milim; et al, CHEMICAL SCIENCE, v.6, no.3, pp.1879 - 1886, 2015-03 |
| Amelioration of amyloid -FcRIIb neurotoxicity and tau pathologies by targeting LYN Gwon, Youngdae; Kim, Seo-Hyun; Kim, Hyun Tae; Kam, Tae-In; Park, Jisu; Lim, Bitna; Cha, Hyunju; et al, FASEB JOURNAL, v.33, no.3, pp.4300 - 4313, 2019-03 |
| Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease Kam, Tae-In; Gwon, Youngdae; Jung, Yong-Keun, CELLULAR AND MOLECULAR LIFE SCIENCES, v.71, no.24, pp.4803 - 4813, 2014-12 |
| Amyloid-beta adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation Korshavn, Kyle J.; Bhunia, Anirban; Lim, Mi Hee; Ramamoorthy, Ayyalusamy, CHEMICAL COMMUNICATIONS, v.52, no.5, pp.882 - 885, 2016-01 |
| An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation Kang, Juhye; Lee, Shin Jung C.; Nam, Jung Seung; Lee, Hyuck Jin; Kang, Myeong-Gyun; Korshavn, Kyle J.; Kim, Hyun-Tak; et al, CHEMISTRY-A EUROPEAN JOURNAL, v.23, no.7, pp.1645 - 1653, 2017-01 |
| Biophysical insights into the membrane interaction of the core amyloid-forming A beta(40) fragment K16-K28 and its role in the pathogenesis of Alzheimer's disease Bera, Swapna; Korshavn, Kyle J.; Kar, Rajiv K.; Lim, Mi Hee; Ramamoorthy, Ayyalusamy; Bhunia, Anirban, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, v.18, no.25, pp.16890 - 16901, 2016-07 |
| Calprotectin Influences the Aggregation of Metal-Free and Metal-Bound Amyloid-β by Direct Interaction Lee, Hyuck Jin; Savelieff, Masha G; Kang, Juhye; Brophy, Megan Brunjes; Nakashige, Toshiki G; Lee, Shin Jung C; Nolan, Elizabeth M; et al, METALLOMICS, v.10, no.8, pp.1116 - 1127, 2018-08 |
| Characterization of copper interactions with Alzheimer amyloid beta peptides: Identification of an attomolar-affinity copper binding site on amyloid beta 1-42 Atwood, Craig S.; Scarpa, Richard C.; Huang, Xudong; Moir, Robert D.; Jones, Walton D; Fairlie, David P.; Tanzi, Rudolph E.; et al, JOURNAL OF NEUROCHEMISTRY, v.75, no.3, pp.1219 - 1233, 2000-09 |
| Characterization of pyridinylimine and pyridinylmethylamine derivatives and their corresponding metal complexese Braymer, Joseph J.; Merrill, Nathan M.; Lim, Mi Hee, INORGANICA CHIMICA ACTA, v.380, pp.261 - 268, 2012-01 |
Chemical strategies to modify amyloidogenic peptides using iridium(iii) complexes: coordination and photo-induced oxidation Kang, Juhye; Nam, Jung Seung; Lee, Hyuck Jin; Nam, Geewoo; Rhee, Hyun-Woo; Kwon, Tae-Hyuk; Lim, Mi Hee, CHEMICAL SCIENCE, v.10, no.28, pp.6855 - 6862, 2019-07 |
| Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta Atwood, Craig S.; Perry, George; Zeng, Hong; Kato, Yoji; Jones, Walton D; Ling, Ke-Qing; Huang, Xudong; et al, BIOCHEMISTRY, v.43, no.2, pp.560 - 568, 2004-01 |
| Current understanding of metal-dependent amyloid-beta aggregation and toxicity Yi, Yelim; Lim, Mi Hee, RSC CHEMICAL BIOLOGY, v.4, no.2, pp.121 - 131, 2023-02 |
| Development of Bifunctional Stilbene Derivatives for Targeting and Modulating Metal-Amyloid-beta Species Braymer, Joseph J.; Choi, Jung-Suk; DeToma, Alaina S.; Wang, Chen; Nam, Kisoo; Kampf, Jeffrey W.; Ramamoorthy, Ayyalusamy; et al, INORGANIC CHEMISTRY, v.50, no.21, pp.10724 - 10734, 2011-11 |
| Drug repurposing: small molecules against Cu(II)-amyloid-beta and free radicals Nam, Geewoo; Suh, Jong-Min; Yi, Yelim; Lim, Mi Hee, JOURNAL OF INORGANIC BIOCHEMISTRY, v.224, pp.111592, 2021-11 |
| Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimers beta-amyloid Kanapathipillai, M; Lentzen, G; Sierks, M; Park, Chan Beum, FEBS LETTERS, v.579, no.21, pp.4775 - 4780, 2005-08 |
| Effects of Clioquinol on Metal-Triggered Amyloid-beta Aggregation Revisited Mancino, Allana M.; Hindo, Sarmad S.; Kochi, Akiko; Lim, Mi Hee, INORGANIC CHEMISTRY, v.48, no.20, pp.9596 - 9598, 2009-10 |
| Exploring the reactivity of flavonoid compounds with metal-associated amyloid-beta species He, Xiaoming; Park, Hyun Min; Hyung, Suk-Joon; DeToma, Alaina S.; Kim, Cheal; Ruotolo, Brandon T.; Lim, Mi Hee, DALTON TRANSACTIONS, v.41, no.21, pp.6558 - 6566, 2012-06 |
| Fc gamma RIIb mediates amyloid-beta neurotoxicity and memory impairment in Alzheimer's disease Kam, Tae-In; Song, Sungmin; Gwon, Youngdae; Park, Hyejin; Yan, Ji-Jing; Im, Isak; Choi, Ji-Woo; et al, JOURNAL OF CLINICAL INVESTIGATION, v.123, no.7, pp.2791 - 2802, 2013-07 |
| Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP Yun, Yee-Jin; Park, Bong-Hwan; Hou, Jingang; Oh, Jung-Pyo; Han, Jin-Hee; Kim, Sun-Chang, LIFE-BASEL, v.12, no.1, 2022-01 |
| Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus Whitcomb, Daniel J.; Hogg, Ellen L.; Regan, Philip; Piers, Thomas; Narayan, Priyanka; Whitehead, Garry; Winters, Bryony L.; et al, SCIENTIFIC REPORTS, v.5, 2015-06 |
| Lysosomal Enzyme Glucocerebrosidase Protects against A beta(1-42) Oligomer-Induced Neurotoxicity Choi, Seulah; Kim, Donghoon; Kam, Tae-In; Yun, Seungpil; Kim, Sangjune; Park, Hyejin; Hwang, Heehong; et al, PLOS ONE, v.10, no.12, 2015-12 |
| Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer’s Disease Han, Jiyeon; Du, Zhi; Lim, Mi Hee, ACCOUNTS OF CHEMICAL RESEARCH, v.54, no.20, pp.3930 - 3940, 2021-10 |
| Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template Ha, Chanki; Ryu, Jungki; Park, Chan Beum, BIOCHEMISTRY, v.46, no.20, pp.6118 - 6125, 2007-05 |
| Metal-associated amyloid-beta species in Alzheimer's disease Pithadia, Amit S.; Lim, Mi Hee, CURRENT OPINION IN CHEMICAL BIOLOGY, v.16, no.1-2, pp.67 - 73, 2012-04 |
| Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease Jones, Michael R.; Mathieu, Emilie; Dyrager, Christine; Faissner, Simon; Vaillancourt, Zavier; Korshavn, Kyle J.; Lim, Mi Hee; et al, CHEMICAL SCIENCE, v.8, no.8, pp.5636 - 5643, 2017-08 |
| Myricetin: A Naturally Occurring Regulator of Metal-Induced Amyloid-beta Aggregation and Neurotoxicity DeToma, Alaina S.; Choi, Jung-Suk; Braymer, Joseph J.; Lim, Mi Hee, CHEMBIOCHEM, v.12, no.8, pp.1198 - 1201, 2011-05 |
| OCIAD2 activates gamma-secretase to enhance amyloid beta production by interacting with nicastrin Han, Jonghee; Jung, Sunmin; Jang, Jiyeon; Kam, Tae-In; Choi, Hyunwoo; Kim, Byung-Ju; Nah, Jihoon; et al, CELLULAR AND MOLECULAR LIFE SCIENCES, v.71, no.13, pp.2561 - 2576, 2014-07 |
| Phagocytic Roles of Glial Cells in Healthy and Diseased Brains Jung, Yeon Joo; Chung, Won-Suk, BIOMOLECULES & THERAPEUTICS, v.26, no.4, pp.350 - 357, 2018-07 |
| Protective effects of asiaticoside derivatives against beta-amyloid neurotoxicity Inhee, MJ; Shin, JE; Yun, SH; Huh, K; Koh, JY; Park, HK; Jew, SS; et al, JOURNAL OF NEUROSCIENCE RESEARCH, v.58, no.3, pp.417 - 425, 1999-11 |
| Reactivities of cyclam derivatives with metal-amyloid-beta Kim, Gunhee; Lelong, Evan; Kang, Juhye; Suh, Jong-Min; Le Bris, Nathalie; Bernard, Helene; Kim, Dongwook; et al, INORGANIC CHEMISTRY FRONTIERS, v.7, no.21, pp.4222 - 4238, 2020-11 |
| Reactivity of Flavonoids Containing a Catechol or Pyrogallol Moiety with Metal-Free and Metal-Associated Amyloid-beta Park, Seongmin; Yi, Yelim; Lim, Mi Hee, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.42, no.1, pp.17 - 24, 2021-01 |
| Redox Properties of Small Molecules Essential for Multiple Reactivities with Pathological Factors in Alzheimer's Disease Kim, Mingeun; Lim, Mi Hee, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.42, no.10, pp.1277 - 1280, 2021-10 |
| Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid- beta Korshavn, Kyle J.; Satriano, Cristina; Lin, Yuxi; Zhang, Rongchun; Dulchavsky, Mark; Bhunia, Anirban; Ivanova, Magdalena I.; et al, JOURNAL OF BIOLOGICAL CHEMISTRY, v.292, no.11, pp.4638 - 4650, 2017-03 |
| Spontaneous Nanobelt Formation by Self-Assembly of beta-Benzyl GABA Jeon, Aram; Gong, Jintaek; Oh, Jun Kyun; Kwon, Sunbum; Lee, Wonchul; Kim, Sang Ouk; Cho, Sung June; et al, CHEMISTRY-AN ASIAN JOURNAL, v.14, no.11, pp.1945 - 1948, 2019-06 |
| Strategic Design of 2,2 '-Bipyridine Derivatives to Modulate Metal Amyloid-beta Aggregation Ji, Yonghwan; Lee, Hyuck Jin; Kim, Minjeong; Nam, Geewoo; Lee, Shin Jung C.; Cho, Jaeheung; Park, Cheol-Min; et al, INORGANIC CHEMISTRY, v.56, no.11, pp.6695 - 6705, 2017-06 |
| Structural Characterization and Inhibition of Toxic Amyloid-beta Oligomeric Intermediates Ramamoorthy, Ayyalusamy; Lim, Mi Hee, BIOPHYSICAL JOURNAL, v.105, no.2, pp.287 - 288, 2013-07 |
| Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease Beck, Michael W.; Derrick, Jeffrey S.; Kerr, Richard A.; Oh, Shin Bi; Cho, Woo Jong; Lee, Shin Jung C.; Ji, Yonghwan; et al, NATURE COMMUNICATIONS, v.7, 2016-10 |
| Tools of the Trade: Investigations into Design Strategies of Small Molecules to Target Components in Alzheimer's Disease Derrick, Jeffrey S.; Lim, Mi Hee, CHEMBIOCHEM, v.16, no.6, pp.887 - 898, 2015-04 |
| Towards an understanding of amyloid-beta oligomers: characterization, toxicity mechanisms, and inhibitors Lee, Shin Jung C.; Nam, Eunju; Lee, Hyuck Jin; Savelieff, Masha G.; Lim, Mi Hee, CHEMICAL SOCIETY REVIEWS, v.46, no.2, pp.310 - 323, 2017-01 |
| Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice Cherny, RA; Atwood, CS; Xilinas, ME; Gray, DN; Jones, Walton D; McLean, CA; Barnham, KJ; et al, NEURON, v.30, no.3, pp.665 - 676, 2001-06 |
| Trehalose differentially inhibits aggregation and neurotoxicity of beta-amyloid 40 and 42 Liu, R; Barkhordarian, H; Emadi, S; Park, Chan Beum; Sierks, MR, NEUROBIOLOGY OF DISEASE, v.20, no.1, pp.74 - 81, 2005-10 |
| Tunable regulatory activities of 1,10-phenanthroline derivatives towards acid sphingomyelinase and Zn(II)–amyloid-b Yi, Yelim; Han, Jiyeon; Park, Min Hee; Park, Nahye; Nam, Eunju; Jin, Hee Kyung; Bae, Jae-Sung; et al, CHEMICAL COMMUNICATIONS, v.55, no.42, pp.5847 - 5850, 2019-05 |
| Tuning Reactivity of Diphenylpropynone Derivatives with Metal-Associated Amyloid-beta Species via Structural Modifications Liu, Yuzhong; Kochi, Akiko; Pithadia, Amit S.; Lee, Sanghyun; Nam, Younwoo; Beck, Michael W.; He, Xiaoming; et al, INORGANIC CHEMISTRY, v.52, no.14, pp.8121 - 8130, 2013-07 |
| Tuning Structures and Properties for Developing Novel Chemical Tools toward Distinct Pathogenic Elements in Alzheimer's Disease Han, Jiyeon; Lee, Hyuck Jin; Kim, Kyu Yeon; Lee, Shin Jung C.; Suh, Jong-Min; Cho, Jaeheung; Chae, Junghyun; et al, ACS CHEMICAL NEUROSCIENCE, v.9, no.4, pp.800 - 808, 2018-04 |
| Untangling Amyloid-beta, Tau, and Metals in Alzheimer's Disease Savelieff, MG; Lee, S; Liu, YZ; Lim, Mi Hee, ACS CHEMICAL BIOLOGY, v.8, no.5, pp.856 - 865, 2013-05 |
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