Controlled Aggregates of Magnetite Nanoparticles for Highly Sensitive MR Contrast Agent

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We have prepared a magnetite encapsulated polymer nanocomposite (MEPN) by an emulsification-diffusion technique and found that the encapsulation efficiency could be precisely controlled according to the portion of magnetite and the capping ligand that covers the surface of the magnetite nanoparticles. The field-dependence and temperature dependence on magnetization, measured by a superconducting quantum interference device, demonstrate that there was no size effect of the magnetite nanoparticles on the encapsulation behavior. The size distribution and T2 relaxivity of prepared MEPNs were measured using magnetic resonance imaging for analysis of the effect of aggregation and it was verified that aggregates of the magnetite nanoparticles provide enhanced relaxation ability.
Publisher
AMER SCIENTIFIC PUBLISHERS
Issue Date
2009-12
Language
English
Article Type
Article; Proceedings Paper
Keywords

DIFFUSION METHOD; MICROSPHERES; NANOCLUSTERS; RELEASE; DRUGS

Citation

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.9, no.12, pp.7118 - 7122

ISSN
1533-4880
DOI
10.1166/jnn.2009.1605
URI
http://hdl.handle.net/10203/99079
Appears in Collection
CBE-Journal Papers(저널논문)
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