DC Field | Value | Language |
---|---|---|
dc.contributor.author | Im, Mae-Soon | ko |
dc.contributor.author | Ahn, Jae-Hyuk | ko |
dc.contributor.author | Han, Jin-Woo | ko |
dc.contributor.author | Park, Tae-Jung | ko |
dc.contributor.author | Lee, Sang-Yup | ko |
dc.contributor.author | Choi, Yang-Kyu | ko |
dc.date.accessioned | 2013-03-11T03:22:55Z | - |
dc.date.available | 2013-03-11T03:22:55Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2011-02 | - |
dc.identifier.citation | IEEE SENSORS JOURNAL, v.11, no.2, pp.351 - 360 | - |
dc.identifier.issn | 1530-437X | - |
dc.identifier.uri | http://hdl.handle.net/10203/98135 | - |
dc.description.abstract | Label-free electrical detection of avian influenza (AI) is demonstrated for the development of a point-of-care testing (POCT) platform. For a new POCT platform, a novel field effect transistor (FET)-based biosensor array was fabricated with conventional complementary metal-oxide-semiconductor (CMOS) technology. Nanogap-embedded separated double-gate FETs (nanogap-DGFETs) were realized in a 6 x 6 array as a biosensor cartridge. Moreover, the low-noise readout circuit was designed and fabricated using a 0.35-mu m standard CMOS process. The AI antigen and antibody were bound with the aid of silica-binding proteins (SBP) in the nanogap of the biosensor device. Because the gate dielectric constant was increased by the immobilized biomolecules, the threshold voltage of the nanogap-DGFET was reduced while the drain-to-source current was enhanced. Drain-to-source currents of the nanogap-DGFET array were successfully acquired using the fabricated readout circuitry and measurement setup. This platform is suitable for a simple and effective label-free detection of AI in POCT applications. | - |
dc.language | English | - |
dc.publisher | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | - |
dc.title | Development of a Point-of-Care Testing Platform With a Nanogap-Embedded Separated Double-Gate Field Effect Transistor Array and Its Readout System for Detection of Avian Influenza | - |
dc.type | Article | - |
dc.identifier.wosid | 000284364500012 | - |
dc.identifier.scopusid | 2-s2.0-78649264150 | - |
dc.type.rims | ART | - |
dc.citation.volume | 11 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 351 | - |
dc.citation.endingpage | 360 | - |
dc.citation.publicationname | IEEE SENSORS JOURNAL | - |
dc.identifier.doi | 10.1109/JSEN.2010.2062502 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Lee, Sang-Yup | - |
dc.contributor.localauthor | Choi, Yang-Kyu | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Avian influenza (AI) | - |
dc.subject.keywordAuthor | biosensor | - |
dc.subject.keywordAuthor | field-effect transistor (FET) | - |
dc.subject.keywordAuthor | nanogap | - |
dc.subject.keywordAuthor | point-of-care testing (POCT) | - |
dc.subject.keywordAuthor | silica-binding proteins (SBP) | - |
dc.subject.keywordPlus | BLOOD ANALYSIS | - |
dc.subject.keywordPlus | ANTIBODY | - |
dc.subject.keywordPlus | VIRUS | - |
dc.subject.keywordPlus | BIOSENSORS | - |
dc.subject.keywordPlus | SENSORS | - |
dc.subject.keywordPlus | PROTEIN | - |
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