Facile Conjugation of Biomolecules onto Surfaces via Mussel Adhesive Protein Inspired Coatings

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A new surface bioconjugation strategy is presented. A polydopamine surface coating provides chemical activation on material surfaces, is resistant to hydrolysis, and offers selectivity in coupling of biomolecules via nucleophilic groups through simple pH control. Control of orientation of immobilized biomolecules may be possible using terminally modified DNA or His-containing proteins.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2009-01
Language
English
Article Type
Article
Citation

ADVANCED MATERIALS, v.21, no.4, pp.431 - 431

ISSN
0935-9648
DOI
10.1002/adma.200801222
URI
http://hdl.handle.net/10203/96993
Appears in Collection
CH-Journal Papers(저널논문)
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