Rh(NHC)-Catalyzed Direct and Selective Arylation of Quinolines at the 8-Position

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A new catalytic protocol for the regioselective direct arylation of quinoline derivatives at the 8-position has been developed. The reaction is catalyzed by a Rh(NHC) system, and the choice of the NHC ligand was most important for achieving high reactivity and selectivity.
Publisher
AMER CHEMICAL SOC
Issue Date
2011-03
Language
English
Article Type
Article
Keywords

C-H BOND; CATALYZED DIRECT ARYLATION; RH(I)-CATALYZED DIRECT ARYLATION; HETEROAROMATIC-COMPOUNDS; DIRHODIUM(II) COMPLEXES; AROMATIC HETEROCYCLES; ARYLBORONIC ACIDS; CARBENE COMPLEXES; ORGANIC-SYNTHESIS; DIRECT AMINATION

Citation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.133, no.11, pp.3780 - 3783

ISSN
0002-7863
DOI
10.1021/ja111670s
URI
http://hdl.handle.net/10203/95273
Appears in Collection
CH-Journal Papers(저널논문)
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