A plasmonic biosensor array by block copolymer lithography

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Highly uniform and dense, hexagonal noble metal nanoparticle arrays were achieved on large-area transparent glass substrates via scalable, parallel processing of block copolymer lithography. Exploring their localized surface plasmon resonance (LSPR) characteristics revealed that the Ag nanoparticle array displayed a UV-vis absorbance spectrum sufficiently narrow and intense for biosensing application. A highly-sensitive, label-free detection of prostate cancer specific antibody (anti-PSA) with sub-ng ml(-1) level detection limit (0.1 similar to 1 ng ml(-1)) has been accomplished with the plasmonic nanostructure. Our approach offers a valuable route to a low-cost, manufacture-scale production of plasmonic nanostructures, potentially useful for various photonic and optoelectronic devices.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2010-09
Language
English
Article Type
Article
Keywords

ENHANCED RAMAN-SCATTERING; NANOSPHERE LITHOGRAPHY; ALZHEIMERS-DISEASE; DIBLOCK COPOLYMER; WAVE-GUIDES; SURFACE; NANOPARTICLES; RESONANCE; BRUSHES; GRAPHOEPITAXY

Citation

JOURNAL OF MATERIALS CHEMISTRY, v.20, no.34, pp.7241 - 7247

ISSN
0959-9428
URI
http://hdl.handle.net/10203/94162
Appears in Collection
MS-Journal Papers(저널논문)
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