Reactions under the Click Chemistry Philosophy Employed in Supramolecular and Mechanostereochemical Systems

Abstract

Supramolecular chemistry and mechanostereo-chemistry have been major beneficiaries of the concepts and reactions pioneered under the "click chemistry" philosophy. The success of the copper(I) 1,3-dipolar cycloaddition between azides and alkynes, resulting in the triazole ring has inspired the application of other emerging click reactions, for example, Diels-Alder cycloadditions, thiolene/yne chemistry, and nitrile N-oxide cycloadditions, to-wards the creation of advanced functional supramolecular and mechanostereochemical systems. In this Focus Review, recent advances in the use of click chemistry in these fields are highlighted.