Bioactive cyanoacrylate-based filling material for bone defects in dental applications

Abstract

tried to prepare a new filling material for bone defects using P-Tricalcium phosphate (beta-TCP) particles and Histoacryl((R)). The aim of this study was to evaluate physical and bioactive properties of cyanoacrylate-based filling materials for bone defects in the dental field. The shear bond strength values of the Histoacryl((R)) and beta-TCP/ Histoacryl((R)) compounds stored in double-distilled water decreased with the increase of the amount of added beta-TCP. The temperature change of the beta-TCP/ Histoacryl((R)) compounds during polymerization decreased compared to that of the Histoacryl((R)). The cytotoxicity of the filling materials decreased when the amount of added P-TCP was increased. In the evaluation of bioactivity, hydroxyapatite (HA) was precipitated on the surface and inner space of the porous filling material 4 weeks after immersion in SBF. This precipitation of HA on the surface of the filling material was also confirmed in the XRD result. These results indicate that our novel beta-TCP/Histoacryl((R)) compounds have the potential to serve as filling materials for bone defects in the dental field.