DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Yong-Kook | ko |
dc.contributor.author | Lee, Hyo-Jong | ko |
dc.contributor.author | Shim, Jung-Jae | ko |
dc.contributor.author | Yeo, Seungeun | ko |
dc.contributor.author | Kim, Seok-Ho | ko |
dc.contributor.author | Koo, Deog-Bon | ko |
dc.contributor.author | Lee, Kyung-Kwang | ko |
dc.contributor.author | Beyhan, Zeki | ko |
dc.contributor.author | First, Neal L. | ko |
dc.contributor.author | Han, Yong Mahn | ko |
dc.date.accessioned | 2013-03-07T14:32:51Z | - |
dc.date.available | 2013-03-07T14:32:51Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2005-05 | - |
dc.identifier.citation | MOLECULAR REPRODUCTION AND DEVELOPMENT, v.71, no.1, pp.29 - 35 | - |
dc.identifier.issn | 1040-452X | - |
dc.identifier.uri | http://hdl.handle.net/10203/90407 | - |
dc.description.abstract | Global reduction of DNA methylation, a part of genome reprogramming processes, occurs in a gradual manner until before implantation and is recognized as a conserved process in mammals. Here, we reported that in bovine, satellite regions exhibited varied patterns of methylation changes when one-cell egg advanced to the blastocyst; a maintenance methylation was observed in satellite I sequences, a decrease in alpha satellites, and an increase in satellite 11 regions. Cloned embryos exhibited similar changes for DNA methylation in the satellite I and alpha. We also observed that the satellite I and a sequences were methylated more in inner cell mass region of the blastocyst whereas the satellite 11 showed selective demethylation in this region. Together, these findings point that individual satellite sequences carry their own methylation patterns under the pressure of global demethylation, suggesting that local methylation control system acts on the satellite regions in early bovine embryos. (c) 2005 Wiley-Liss, Inc. | - |
dc.language | English | - |
dc.publisher | WILEY-LISS | - |
dc.subject | MAMMALIAN DEVELOPMENT | - |
dc.subject | CLONED EMBRYOS | - |
dc.subject | MOUSE | - |
dc.subject | DEMETHYLATION | - |
dc.subject | GENOME | - |
dc.title | Varied patterns of DNA methylation change between different satellite regions in bovine preimplantation development | - |
dc.type | Article | - |
dc.identifier.wosid | 000228037600004 | - |
dc.identifier.scopusid | 2-s2.0-20144387939 | - |
dc.type.rims | ART | - |
dc.citation.volume | 71 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 29 | - |
dc.citation.endingpage | 35 | - |
dc.citation.publicationname | MOLECULAR REPRODUCTION AND DEVELOPMENT | - |
dc.identifier.doi | 10.1002/mrd.20249 | - |
dc.contributor.localauthor | Han, Yong Mahn | - |
dc.contributor.nonIdAuthor | Kang, Yong-Kook | - |
dc.contributor.nonIdAuthor | Lee, Hyo-Jong | - |
dc.contributor.nonIdAuthor | Shim, Jung-Jae | - |
dc.contributor.nonIdAuthor | Yeo, Seungeun | - |
dc.contributor.nonIdAuthor | Kim, Seok-Ho | - |
dc.contributor.nonIdAuthor | Koo, Deog-Bon | - |
dc.contributor.nonIdAuthor | Lee, Kyung-Kwang | - |
dc.contributor.nonIdAuthor | Beyhan, Zeki | - |
dc.contributor.nonIdAuthor | First, Neal L. | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | bovine | - |
dc.subject.keywordAuthor | preimplantation embryo | - |
dc.subject.keywordAuthor | DNA methylation | - |
dc.subject.keywordAuthor | demethylation | - |
dc.subject.keywordAuthor | satellite sequences | - |
dc.subject.keywordPlus | MAMMALIAN DEVELOPMENT | - |
dc.subject.keywordPlus | CLONED EMBRYOS | - |
dc.subject.keywordPlus | MOUSE | - |
dc.subject.keywordPlus | DEMETHYLATION | - |
dc.subject.keywordPlus | GENOME | - |
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