DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, S | ko |
dc.contributor.author | Kim, J | ko |
dc.contributor.author | Cho, Kwang-Hyun | ko |
dc.date.accessioned | 2013-03-06T22:54:59Z | - |
dc.date.available | 2013-03-06T22:54:59Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2007-08 | - |
dc.identifier.citation | COMPUTATIONAL BIOLOGY AND CHEMISTRY, v.31, pp.239 - 245 | - |
dc.identifier.issn | 1476-9271 | - |
dc.identifier.uri | http://hdl.handle.net/10203/88751 | - |
dc.description.abstract | Ordinary differential equations (ODE) have been widely used for modeling and analysis of dynamic gene networks in systems biology. In this paper, we propose an optimization method that can infer a gene regulatory network from time-series gene expression data. Specifically, the following four cases are considered: (1) reconstruction of a gene network from synthetic gene expression data with noise, (2) reconstruction of a Dene network from synthetic gene expression data with time-delay, (3) reconstruction of a gene network from synthetic gene expression data with noise and time-delay, and (4) reconstruction of a gene network from experimental time-series data in budding yeast cell cycle. (c) 2007 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | EXPONENTIAL STABILITY | - |
dc.subject | NEURAL-NETWORKS | - |
dc.subject | PERTURBATIONS | - |
dc.subject | YEAST | - |
dc.title | Inferring gene regulatory networks from temporal expression profiles under time-delay and noise | - |
dc.type | Article | - |
dc.identifier.wosid | 000249192700001 | - |
dc.identifier.scopusid | 2-s2.0-34447651339 | - |
dc.type.rims | ART | - |
dc.citation.volume | 31 | - |
dc.citation.beginningpage | 239 | - |
dc.citation.endingpage | 245 | - |
dc.citation.publicationname | COMPUTATIONAL BIOLOGY AND CHEMISTRY | - |
dc.identifier.doi | 10.1016/j.compbiolchem.2007.03.013 | - |
dc.contributor.localauthor | Cho, Kwang-Hyun | - |
dc.contributor.nonIdAuthor | Kim, S | - |
dc.contributor.nonIdAuthor | Kim, J | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | gene networks | - |
dc.subject.keywordAuthor | inference | - |
dc.subject.keywordAuthor | optimization | - |
dc.subject.keywordAuthor | ordinary differential equations | - |
dc.subject.keywordAuthor | noise | - |
dc.subject.keywordAuthor | time-delay | - |
dc.subject.keywordPlus | EXPONENTIAL STABILITY | - |
dc.subject.keywordPlus | NEURAL-NETWORKS | - |
dc.subject.keywordPlus | PERTURBATIONS | - |
dc.subject.keywordPlus | YEAST | - |
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