PEMFC (Proton Exchange Membrane Fuel Cell) is a low temperature fuel cell and possible to start up quickly compared with other fuel cells. For this reason, researchers emphasize on PEMFC as a substitute for the internal combustion engine in automobiles. However, water management in PEMFC is the most intricate part and needs to be analyzed. Parameters related with water management are important because they are main factors and conclude the performance of PEMFC. In this study, flow directions of the reactants in anode and cathode channels have investigated. It has found that reactants flow direction significantly influences the water behavior in PEMFC. Moreover, local current density and overpotential distribution has shown that the cell performance can be improved with better water management by changing the flow directions.