DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Kyoung Sang | ko |
dc.contributor.author | Kim, Joon Ki | ko |
dc.contributor.author | Yu, Si Young | ko |
dc.contributor.author | Hong, Yoon Ki | ko |
dc.contributor.author | Koh, Hyongjong | ko |
dc.contributor.author | Chung, Jongkyeong | ko |
dc.date.accessioned | 2013-03-06T21:04:04Z | - |
dc.date.available | 2013-03-06T21:04:04Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2007-06 | - |
dc.identifier.citation | KOREAN JOURNAL OF GENETICS, v.29, no.2, pp.203 - 210 | - |
dc.identifier.issn | 0254-5934 | - |
dc.identifier.uri | http://hdl.handle.net/10203/88453 | - |
dc.description.abstract | Mating increases protein synthesis in the Drosophila male accessory glands. To elucidate the components involved in the stimulation of protein synthesis, mating-induced phosphorylation of accessory gland proteins was examined. Mating prominently stimulates the phosphorylation of two proteins (Mr 20,000 and 30,000), which are inferred to be Drosophila eIF-4E binding protein (d4E-BP) and ribosomal protein S6. The stimulated phosphorylation corresponded with protein synthesis, and was inhibited by rapamycin and wortmannin. Furthermore, mating increased phosphorylation of d4E-BP and S6, the dissociation of d4E-BP from eIF-4E, and S6 kinase activity. Collectively, these findings suggest that d4E-BP and S6 mediate the stimulation of protein synthesis by mating in Drosophila. | - |
dc.language | English | - |
dc.publisher | GENETICS SOC KOREA | - |
dc.subject | INITIATION-FACTOR 4E | - |
dc.subject | PHOSPHOINOSITIDE 3-KINASE | - |
dc.subject | TRANSLATION INITIATION | - |
dc.subject | ECTOPIC EXPRESSION | - |
dc.subject | SIGNALING PATHWAY | - |
dc.subject | GENE-EXPRESSION | - |
dc.subject | INSULIN | - |
dc.subject | KINASE | - |
dc.subject | GROWTH | - |
dc.subject | CELLS | - |
dc.title | Mating stimulates protein phosphorylation and synthesis via rapamycin- and wortmannin-sensitive pathways in the male accessory glands of D-melanogaster | - |
dc.type | Article | - |
dc.identifier.wosid | 000248132700012 | - |
dc.identifier.scopusid | 2-s2.0-34447638877 | - |
dc.type.rims | ART | - |
dc.citation.volume | 29 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 203 | - |
dc.citation.endingpage | 210 | - |
dc.citation.publicationname | KOREAN JOURNAL OF GENETICS | - |
dc.contributor.localauthor | Chung, Jongkyeong | - |
dc.contributor.nonIdAuthor | Cho, Kyoung Sang | - |
dc.contributor.nonIdAuthor | Kim, Joon Ki | - |
dc.contributor.nonIdAuthor | Yu, Si Young | - |
dc.contributor.nonIdAuthor | Hong, Yoon Ki | - |
dc.contributor.nonIdAuthor | Koh, Hyongjong | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | 4E-BP | - |
dc.subject.keywordAuthor | accessory glands | - |
dc.subject.keywordAuthor | Drosophila melanogaster | - |
dc.subject.keywordAuthor | mating | - |
dc.subject.keywordAuthor | protein synthesis | - |
dc.subject.keywordAuthor | S6 | - |
dc.subject.keywordPlus | INITIATION-FACTOR 4E | - |
dc.subject.keywordPlus | PHOSPHOINOSITIDE 3-KINASE | - |
dc.subject.keywordPlus | TRANSLATION INITIATION | - |
dc.subject.keywordPlus | ECTOPIC EXPRESSION | - |
dc.subject.keywordPlus | SIGNALING PATHWAY | - |
dc.subject.keywordPlus | GENE-EXPRESSION | - |
dc.subject.keywordPlus | INSULIN | - |
dc.subject.keywordPlus | KINASE | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | CELLS | - |
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