DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yi, S. | ko |
dc.contributor.author | Cho, Young-Ho | ko |
dc.date.accessioned | 2013-03-06T14:24:10Z | - |
dc.date.available | 2013-03-06T14:24:10Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2006-08 | - |
dc.identifier.citation | CURRENT APPLIED PHYSICS, v.6, no.1, pp.e72 - e75 | - |
dc.identifier.issn | 1567-1739 | - |
dc.identifier.uri | http://hdl.handle.net/10203/87242 | - |
dc.description.abstract | This paper presents the experimental study to realize a DNA separation chip based on the self-focusing effect in a micropillar array. The present self-focusing chip redistributes DNA molecules within a specific area of micropillar arrays based on the size- and field-dependent nonlinearity of DNA drift velocity. Compared to conventional electrophoresis chips, the present self-focusing chip reduces a substantial amount of the separation channel length, the influence of sample starting location, and the necessity of time-consuming continuous monitoring process. We focus on the design of DNA self-focusing chips, with identifying the nonlinearity of DNA drift velocity using three different DNA molecules including λ DNA(48.5 kbp), micrococcus DNA(115 kbp), and T4 DNA(169.8 kbp) in microfabricated test chips. It is demonstrated that the present DNA self-focusing chips have potentials not only for the miniaturization of DNA analysis systems, but also for the tunable capability of the target DNA size to be separated, trapped and extracted. ? 2006 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | Elsevier BV | - |
dc.title | Self-focusing DNA separation chips using micropillar array with nonuniformly distributed asymmetric electric fields | - |
dc.type | Article | - |
dc.identifier.wosid | 000209752200016 | - |
dc.identifier.scopusid | 2-s2.0-33746266674 | - |
dc.type.rims | ART | - |
dc.citation.volume | 6 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | e72 | - |
dc.citation.endingpage | e75 | - |
dc.citation.publicationname | CURRENT APPLIED PHYSICS | - |
dc.identifier.doi | 10.1016/j.cap.2006.01.015 | - |
dc.contributor.localauthor | Cho, Young-Ho | - |
dc.contributor.nonIdAuthor | Yi, S. | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Bio-separators | - |
dc.subject.keywordAuthor | DNA self-focusing chips | - |
dc.subject.keywordAuthor | Electrophoresis | - |
dc.subject.keywordAuthor | Nonuniformly distributed asymmetric electric fields | - |
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