DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sung Gak | ko |
dc.date.accessioned | 2013-03-04T08:32:39Z | - |
dc.date.available | 2013-03-04T08:32:39Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2003-08 | - |
dc.identifier.citation | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.125, no.32, pp.9682 - 9688 | - |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | http://hdl.handle.net/10203/82181 | - |
dc.description.abstract | 3-tert-Butyldimethylsilyloxyalk-2-enyisulfonium salts, generated in situ from the reaction of alpha, beta-enones with dimethyl sulfide in the presence of TBSOTf, underwent a novel nucleophilic substitution with allylindiums to give silyl enol ethers of delta, epsilon-alkenyl ketones in good yields, which correspond to formal Michael addition products. In a similar manner, 1,4-propargylation of propargylindiums onto the sulfonium salts produced the corresponding silyl enol ethers of delta, epsilon-alkynyl ketones in good yields. Organoindium reagents derived from gamma-substituted propargyl bromide and indium afforded the corresponding silyl enol ethers of beta-allenyl ketones in good yields. The reaction proceeds via an addition-substitution mechanism involving the formation of allylic sulfonium salts. The presence of the intermediate sulfonium salt was confirmed by observation of the low-temperature H-1 NMR spectra. | - |
dc.language | English | - |
dc.publisher | Amer Chemical Soc | - |
dc.subject | SILYL ENOL ETHERS | - |
dc.subject | CROSS-COUPLING REACTIONS | - |
dc.subject | AQUEOUS-MEDIA | - |
dc.subject | CARBONYL-COMPOUNDS | - |
dc.subject | REFORMATSKY REACTION | - |
dc.subject | ALLYLINDIUM REAGENTS | - |
dc.subject | CONJUGATE ADDITION | - |
dc.subject | NUCLEOPHILIC-SUBSTITUTION | - |
dc.subject | ORGANOMETALLIC REACTIONS | - |
dc.subject | CYCLOPENTENE ANNULATION | - |
dc.title | Indium-Mediated β-Allylation, β-Propagylation, and β-Allenylation onto α,β- Unsaturated Ketones: Reaction of in-Situ-Generated 3-t-Butyldimethyl-sily | - |
dc.type | Article | - |
dc.identifier.wosid | 000184654700043 | - |
dc.identifier.scopusid | 2-s2.0-0042125246 | - |
dc.type.rims | ART | - |
dc.citation.volume | 125 | - |
dc.citation.issue | 32 | - |
dc.citation.beginningpage | 9682 | - |
dc.citation.endingpage | 9688 | - |
dc.citation.publicationname | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | - |
dc.contributor.localauthor | Kim, Sung Gak | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | SILYL ENOL ETHERS | - |
dc.subject.keywordPlus | CROSS-COUPLING REACTIONS | - |
dc.subject.keywordPlus | AQUEOUS-MEDIA | - |
dc.subject.keywordPlus | CARBONYL-COMPOUNDS | - |
dc.subject.keywordPlus | REFORMATSKY REACTION | - |
dc.subject.keywordPlus | ALLYLINDIUM REAGENTS | - |
dc.subject.keywordPlus | CONJUGATE ADDITION | - |
dc.subject.keywordPlus | NUCLEOPHILIC-SUBSTITUTION | - |
dc.subject.keywordPlus | ORGANOMETALLIC REACTIONS | - |
dc.subject.keywordPlus | CYCLOPENTENE ANNULATION | - |
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