General and facile synthesis of 1,2-amino alcohols

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Facile preparation of 1,2-amino alcohols has been achieved by the reaction of benzyloxymethyl lithium with imines, which are generated from alpha-amido sulfones and benzyloxymethyl lithium in situ at -78degreesC in THF.
Publisher
GEORG THIEME VERLAG KG
Issue Date
2004-06
Language
English
Article Type
Article
Keywords

BETA-AMINO ALCOHOLS; ASYMMETRIC-SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; ORGANOMETALLIC REAGENTS; ACIDS; INHIBITOR; HYDRAZONES; EFFICIENT; ALDEHYDES

Citation

SYNLETT, no.7, pp.1315 - 1317

ISSN
0936-5214
DOI
10.1055/s-2004-822926
URI
http://hdl.handle.net/10203/82096
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