DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, CB | ko |
dc.contributor.author | Kim, MS | ko |
dc.contributor.author | Kim, Sun-Chang | ko |
dc.date.accessioned | 2013-03-02T18:40:45Z | - |
dc.date.available | 2013-03-02T18:40:45Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1996-01 | - |
dc.identifier.citation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.218, no.1, pp.408 - 413 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.uri | http://hdl.handle.net/10203/74951 | - |
dc.description.abstract | A potent and structurally novel antimicrobial peptide was isolated and characterized from the stomach tissue of Bufo bufo gargarizans, an Asian toad. The 39-amino acid peptide, named buforin I, was purified to homogeneity by heparin-affinity column and reverse-phase HPLC. The amino acid sequence of buforin I was identical in 37 of 39 amino-terminal residues of Xenopus histone H2A. The buforin I showed strong antimicrobial activities in vitro against a broad-spectrum of microorganisms and was found to be more potent than magainin 2. In addition, a 21-amino acid peptide, named buforin II, which was derived from buforin I, showed more potent antimicrobial activities than buforin I. (C) 1996 Academic Press, Inc. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE | - |
dc.subject | ANTIBIOTIC PEPTIDES | - |
dc.subject | LIPID BILAYERS | - |
dc.subject | MAGAININ-2 | - |
dc.subject | CHANNELS | - |
dc.subject | SKIN | - |
dc.title | A novel antimicrobial peptide from Bufo bufo gargarizans | - |
dc.type | Article | - |
dc.identifier.wosid | A1996TP75400071 | - |
dc.identifier.scopusid | 2-s2.0-0030068934 | - |
dc.type.rims | ART | - |
dc.citation.volume | 218 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 408 | - |
dc.citation.endingpage | 413 | - |
dc.citation.publicationname | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.identifier.doi | 10.1006/bbrc.1996.0071 | - |
dc.contributor.localauthor | Kim, Sun-Chang | - |
dc.contributor.nonIdAuthor | Park, CB | - |
dc.contributor.nonIdAuthor | Kim, MS | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ANTIBIOTIC PEPTIDES | - |
dc.subject.keywordPlus | LIPID BILAYERS | - |
dc.subject.keywordPlus | MAGAININ-2 | - |
dc.subject.keywordPlus | CHANNELS | - |
dc.subject.keywordPlus | SKIN | - |
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