Highly diastereoselective addition of trimethylsilyl cyanide to chiral hydrazones in the presence of Et(2)AlCl
Chiral hydrazones, synthesized from (S)-1-amino-2-methoxymethylindoline and aliphatic aldehydes, reacted with trimethylsilyl cyanide in the presence of diethylaluminium chloride in CH2Cl2 at -78 degrees C to give chiral alpha-hydrazinonitriles with high diastereoselectivity (up to 96% de). Copyright (C) 1996 Elsevier Science Ltd.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 1996-10
- Language
- English
- Article Type
- Article
- Keywords
AMINO-ACIDS; STRECKER SYNTHESIS; SCHIFF-BASES
- Citation
TETRAHEDRON LETTERS, v.37, no.43, pp.7795 - 7796
- ISSN
- 0040-4039
- Appears in Collection
- Files in This Item
- There are no files associated with this item.
This item is cited by other documents in WoS
| ⊙ Detail Information in WoSⓡ | Click to see |  |
| ⊙ Cited 20 items in WoS | Click to see citing articles in |  |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.