TOTAL SYNTHESIS OF D-(+)-SHOWDOMYCIN FROM SYN-2,5,-DISUBSTITUTED TETRAHYDROFURAN
D-(+)-Showdomycin, first isolated from Streptomyces showdoensis, has been synthesized starting from syn-2,5-disubstituted dihydrofuran 3. The key conversion was the functionalization of 2-thiophenylfuranyl group in 13 into maleic acid moiety in 12.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 1995-06
- Language
- English
- Article Type
- Article
- Keywords
STEREOCONTROLLED SYNTHESIS; SHOWDOMYCIN
- Citation
TETRAHEDRON LETTERS, v.36, no.23, pp.4089 - 4092
- ISSN
- 0040-4039
- Appears in Collection
- CH-Journal Papers(저널논문)
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