Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths
We characterized evolutionarily conserved J domain containing protein (JDP) genes from human, Bombyx mori, and Manduca sexta. Each of the JDP proteins contains a J domain at its N-terminus and a highly conserved C-terminal domain. Southern blot analysis revealed that the human JDP1 gene is present as a single copy in the human genome. Expression was higher in brain, heart, and testis than in kidney or stomach. Human JDP1 was mapped in silico to chromosome 10q21.1, which exhibits a conserved synteny with the central region of mouse chromosome 10. Drosophila jdp is located at 99F4-99F11 on the right arm of the third chromosome. (C) 2000 Elsevier Science B.V. All rights reserved.
- Publisher
- ELSEVIER SCIENCE BV
- Issue Date
- 2000-04
- Language
- English
- Article Type
- Article
- Keywords
ESCHERICHIA-COLI DNAJ; HEAT-SHOCK PROTEIN; HUMAN HOMOLOG; BACTERIAL DNAJ; CHAPERONE; YEAST; HSP70; GENOME
- Citation
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, v.1491, no.1-3, pp.355 - 363
- ISSN
- 0167-4781
- Appears in Collection
- BS-Journal Papers(저널논문)
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