For the strategic management of the small and/or mid sized clinics, the introduction of the clinic information system is necessary. Currently there are not many information systems for the clinics, yet. In this study, we have developed a clinic information system (CLINSYS) as a guiding prototype and suggested the development directions of the total integrated clinic decision support system. For the better user interface and easy communication. the object-oriented language Macintosh Hyper-Card and Excel are used as the developing tools. And as a part of the integrated decision system, an expert system to consult about the urine test and the blood test interpretation has been developed using the Macintosh spreadsheet Excel.