Since electronic switching systems usually require very strict reliability requirements as well as good performance objectives, we need to jointly analyse the performance and reliability of switching systems. In this paper, we compare conventional time-space-time switches with single space switches with those with multiple separated space switches, from the viewpoints of reliability and performance. We consider time-space-time switching networks which consist of N incoming time switches, i.e. one N × N space switch, two (N/2) × (N/2) space switches, and four (N/4) × (N/4) space switches. We introduce a Markov reliability model to study the effect of failures and analyse the reliability and performance of three different types of switching networks in terms of average blocking probability and the mean time to unreliable operation, as we vary the offered traffic. As a result, T-S-T switching networks with multiple separated space switches exhibit better performance and reliability than those with single space switches.