DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Gyun Min | ko |
dc.contributor.author | Choi, CY | ko |
dc.contributor.author | Park, JM | ko |
dc.contributor.author | Han, MH | ko |
dc.date.accessioned | 2013-02-25T14:33:48Z | - |
dc.date.available | 2013-02-25T14:33:48Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1985-03 | - |
dc.identifier.citation | JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. BIOTECHNOLOGY, v.35 B, no.1, pp.3 - 10 | - |
dc.identifier.issn | 0264-3421 | - |
dc.identifier.uri | http://hdl.handle.net/10203/62884 | - |
dc.description.abstract | The biotransformation of rifamycin B to rifamycin S using immobilised whole cells of a Humicola sp. in a fluidised bed reactor exhibited a linear relationship between loading of the immobilised whole cells and conversion, in both batch and continuous operations; the conversion of rifamycin B was higher in batch than continuous operation for a given residence time. The immobilised whole cells were obtained by copolymerisation of the acetone-dried cells with acrylamide. They showed maximum activity of pH 7.8 and 50°C. It was found that aeration effects on the reaction in continuous operation were different from those in batch operation for the same residence time. In batch operation, the conversion of rifamycin B to rifamycin S increased with increased rate of aeration and reached a constant maximum value at aeration rates above 20.8 vvm. In continuous operation, the steady state conversion reached a maximum value in the range of aeration rate between 5.8 and 12.5 vvm; beyond this range the steady state conversion decreased steadily owing to cell leakage. The half life for the operational stability at 40°C was about 13 h. | - |
dc.language | English | - |
dc.publisher | Blackwell Publishing | - |
dc.title | BIOTRANSFORMATION OF RIFAMYCIN-B TO RIFAMYCIN-S USING IMMOBILIZED WHOLE CELLS OF HUMICOLA SPP IN A FLUIDIZED-BED REACTOR | - |
dc.type | Article | - |
dc.identifier.wosid | A1985AFE6200002 | - |
dc.identifier.scopusid | 2-s2.0-0022039653 | - |
dc.type.rims | ART | - |
dc.citation.volume | 35 B | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 3 | - |
dc.citation.endingpage | 10 | - |
dc.citation.publicationname | JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. BIOTECHNOLOGY | - |
dc.contributor.localauthor | Lee, Gyun Min | - |
dc.contributor.nonIdAuthor | Choi, CY | - |
dc.contributor.nonIdAuthor | Park, JM | - |
dc.contributor.nonIdAuthor | Han, MH | - |
dc.type.journalArticle | Article | - |
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