DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeong, T.C. | ko |
dc.contributor.author | Jeong, H.G. | ko |
dc.contributor.author | Yang, Kyu Hwan | ko |
dc.date.accessioned | 2013-02-25T04:06:53Z | - |
dc.date.available | 2013-02-25T04:06:53Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1992-07 | - |
dc.identifier.citation | TOXICOLOGY LETTERS, v.61, no.2-3, pp.275 - 281 | - |
dc.identifier.issn | 0378-4274 | - |
dc.identifier.uri | http://hdl.handle.net/10203/59722 | - |
dc.description.abstract | Treatment of hepatocyte cultures with dimethyl sulfoxide (DMSO) induced P-450IIE1-specific aniline 4-hydroxylase activity and P-450IA1-specific ethoxyresorufin O-deethylase activity at a concentration of 0.1 % (v/v). The P-450IIB-specific pentoxyresorufin O-dealkylase activity was induced only at the 2% (v/v) level. Dot blot analysis of the total cellular RNA and cycloheximide treatment of the culture suggested that induction of ethoxyresorufin O-deethylase activity by DMSO may be due to the increase of de novo synthesis of the P-450IA1 protein, not to accumulation of mRNA in the hepatocyte culture. | - |
dc.language | English | - |
dc.publisher | Elsevier Ireland Ltd | - |
dc.subject | N-NITROSODIMETHYLAMINE DEMETHYLASE | - |
dc.subject | MAINTENANCE | - |
dc.subject | LIVER | - |
dc.subject | ACETONE | - |
dc.subject | GENES | - |
dc.subject | DMSO | - |
dc.title | Induction of cytochrome P-450 by dimethyl sulfoxide in primary cultures of adult rat hepatocytes | - |
dc.type | Article | - |
dc.identifier.wosid | A1992JG05100016 | - |
dc.identifier.scopusid | 2-s2.0-0026710432 | - |
dc.type.rims | ART | - |
dc.citation.volume | 61 | - |
dc.citation.issue | 2-3 | - |
dc.citation.beginningpage | 275 | - |
dc.citation.endingpage | 281 | - |
dc.citation.publicationname | TOXICOLOGY LETTERS | - |
dc.contributor.nonIdAuthor | Jeong, T.C. | - |
dc.contributor.nonIdAuthor | Jeong, H.G. | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | DIMETHYL SULFOXIDE | - |
dc.subject.keywordAuthor | INDUCTION OF CYTOCHROME-P-450 | - |
dc.subject.keywordAuthor | HEPATOCYTE CULTURE | - |
dc.subject.keywordPlus | N-NITROSODIMETHYLAMINE DEMETHYLASE | - |
dc.subject.keywordPlus | MAINTENANCE | - |
dc.subject.keywordPlus | LIVER | - |
dc.subject.keywordPlus | ACETONE | - |
dc.subject.keywordPlus | GENES | - |
dc.subject.keywordPlus | DMSO | - |
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