A SHORT SYNTHESIS OF 3(R)-HYDROXY-2(R)-ISOPROPYLTETRAHYDROTHIOPHENE - A PRECURSOR TO A HIGH-AFFINITY P2-LIGAND OF HIV-1 PROTEASE INHIBITORS
The title compound was synthesized in a 6 step sequence involving an efficient lipase-mediated resolution of racemic 3-hydroxy-2-isopropyltetrahydrothiophene.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 1993-10
- Language
- English
- Article Type
- Article
- Keywords
PSEUDOMONAS-FLUORESCENS LIPASE; ENZYMATIC PREPARATION; ENZYMES
- Citation
TETRAHEDRON LETTERS, v.34, no.41, pp.6517 - 6520
- ISSN
- 0040-4039
- Appears in Collection
- CH-Journal Papers(저널논문)
- Files in This Item
- There are no files associated with this item.
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