A STEREOCONTROLLED SYNTHESIS OF A KEY INTERMEDIATE TO (+)-THIENAMYCIN
A formal synthesis of (+)-thienamycin was achieved by the enantioselective preparation of key intermediate azetidinone 2 [benzyl (2R,3S)-3-{(S)-1-hydroxyethyl}-4-oxo-2-azetidineacetate] via an intramolecular nitrone 1,3-dipolar cycloaddition.
- Publisher
- GEORG THIEME VERLAG
- Issue Date
- 1991-07
- Language
- English
- Article Type
- Note
- Keywords
DEHYDROPEPTIDASE-I; RENAL DIPEPTIDASE; THIENAMYCIN; ANTIBIOTICS; OXIDATION; ACIDS
- Citation
SYNLETT, no.7, pp.520 - 522
- ISSN
- 0936-5214
- Appears in Collection
- CH-Journal Papers(저널논문)
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