Browse "Dept. of Chemistry(화학과)" by Subject POTENT

Showing results 1 to 27 of 27

1
Application of Fragment-Based de Novo Design to the Discovery of Selective Picomolar Inhibitors of Glycogen Synthase Kinase-3 Beta

Park, Hwangseo; Shin, Yongje; Kim, Jinhee; Hong, Sungwoo, JOURNAL OF MEDICINAL CHEMISTRY, v.59, no.19, pp.9018 - 9034, 2016-10

2
Computational Design and Discovery of Nanomolar Inhibitors of I kappa B Kinase beta

Park, Hwangseo; Shin, Yong Je; Choe, Hyeonjeong; Hong, Sung-Woo, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.1, pp.337 - 348, 2015-01

3
Construction of a Library of Arylpiperazinyl 1,2,3-Triazole Derivatives as Ligands for Dopamine D-3/D-4 Receptor

Kwak, Ju Myung; Moon, Ji Soo; Choi, Jea I.; MURUGAN RAVICHANDRAN, NARAYANASAMY; Park, Woo Kyu; Gong, Jae Yang; Lee, Hee Yoon; et al, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.34, no.11, pp.3467 - 3470, 2013-11

4
Crystal structure of phosphodiesterase 4D and inhibitor complex

Lee, ME; Markowitz, J; Lee, Jie-Oh; Lee, H, FEBS LETTERS, v.530, no.1-3, pp.53 - 58, 2002-10

5
Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands

Cha, MY; Choi, BC; Kang, KH; Pae, AN; Choi, KI; Cho, YS; Koh, HY; et al, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.12, no.10, pp.1327 - 1330, 2002-05

6
Design and Synthesis of Imidazopyridine Analogues as Inhibitors of Phosphoinositide 3-Kinase Signaling and Angiogenesis

Kim, O; Jeong, Y; Lee, H; Hong, SS; Hong, Sungwoo, JOURNAL OF MEDICINAL CHEMISTRY, v.54, no.7, pp.2455 - 2466, 2011-04

7
Design, Synthesis and Antiviral Activity of 5-Hydroxymethyl-3-phosphonyl-4,5-dihydrofuran Analogs of Nucleotides

Lee, Hee Yoon; Lee, Kiho; Hah, Jung Hwan; Moon, Deuk Kyu; Lee, Chong-Kyo, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.31, no.8, pp.2139 - 2140, 2010-08

8
Development of Non-peptidic Farnesyltransferase Inhibitors based on the Ca(1)a(2) of Ras-CaaX

Lee, Hee Yoon; Chun, Tae-Gyu; Choi, Hyun-Moo; Sohn, Jeong-Hun; Kwon, Byoung-Mog, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.30, no.2, pp.291 - 292, 2009-02

9
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products

Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.293 - 299, 2016-02

10
Discovery of Low Micromolar Dual Inhibitors for Wild Type and L1196M Mutant of Anaplastic Lymphoma Kinase through Structure-Based Virtual Screening

Shin, Saemina; Mah, Shinmee; Hong, Sungwoo; Park, Hwangseo, JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.56, no.4, pp.802 - 810, 2016-04

11
Discovery of new azaindole-based PI3K alpha inhibitors: Apoptotic and antiangiogenic effect on cancer cells

Hong, S; Lee, S; Kim, B; Lee, H; Hong, SS; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.20, no.24, pp.7212 - 7215, 2010-12

12
Discovery of wrightiadione as a novel template for the TrkA kinase inhibitors

Jeong, Yujeong; Lim, Sang Min; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.22, pp.5186 - 5189, 2015-11

13
Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1

Lee, Yujeong; Onishi, Yoshiyuki; McPherson, Lisa; Kietrys, Anna M.; Hebenbrock, Marian; Jun, Yong Woong; Das, Ishani; et al, ACS CHEMICAL BIOLOGY, v.17, no.8, pp.2074 - 2087, 2022-07

14
Identification of novel BRAF kinase inhibitors with structure-based virtual screening

Park, H; Choi, H; Hong, S; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.21, no.19, pp.5753 - 5756, 2011-10

15
Nonpeptidal P-2 ligands for HIV protease inhibitors: Structure-based design, synthesis, and biological evaluation

Ghosh, AK; Kincaid, JF; Walters, DE; Chen, Y; Chaudhuri, NC; Thompson, WJ; Culberson, C; et al, JOURNAL OF MEDICINAL CHEMISTRY, v.39, no.17, pp.3278 - 3290, 1996-08

16
Stereoretentive cross-coupling of chiral amino acid chlorides and hydrocarbons through mechanistically controlled Ni/Ir photoredox catalysis

Lee, Geun Seok; Park, Beomsoon; Hong, Soon Hyeok, NATURE COMMUNICATIONS, v.13, no.1, 2022-09

17
Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors

Park, Hwangseo; Jeong, Yujeong; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.22, no.2, pp.1027 - 1030, 2012-01

18
Structure-based de novo design and synthesis of aminothiazole-based p38 MAP kinase inhibitors

Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.18, pp.3784 - 3787, 2015-09

19
Structure-based design of flavone-based inhibitors of wild-type and T315I mutant of ABL

Choe, Hyeonjeong; Kim, Jieun; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.23, no.15, pp.4324 - 4327, 2013-08

20
Structure-based virtual screening approach to the discovery of p38 MAP kinase inhibitors

Choi, Hwanho; Park, Ho Jeong; Shin, Jong Chul; Ko, Hyun Sun; Lee, Jung Kyun; Lee, Soyoung; Park, Hwangseo; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.6, pp.2195 - 2199, 2012-03

21
Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors

Ahn, Jin Hee; Park, Woul Seong; Jun, Mi Ae; Shin, Mi Sik; Kang, Seung Kyu; Kim, Ki Young; Dal Rhee, Sang; et al, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.18, no.24, pp.6525 - 6529, 2008-12

22
Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors

Park, WS; Kang, SK; Kim, KY; Kim, KR; Dal Rhee, S; Bae, MA; Kang, NS; et al, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.43, no.9, pp.1889 - 1902, 2008-09

23
Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidlyl peptidase IV (DPP-IV) inhibitors

Ahn, Jin Hee; Shin, Mi Sik; Jun, Mi Ae; Jung, Sun Ho; Kang, Seung Kyu; Kim, Kwang Rok; Dal Rhee, Sang; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.17, no.9, pp.2622 - 2628, 2007-05

24
Synthesis, enzymatic inhibition, and cancer cell growth inhibition of novel delta-lactam-based histone deacetylase (HDAC) inhibitors

Kim, HM; Lee, K; Park, BW; Ryu, DK; Kim, K; Lee, CW; Park, SK; et al, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.16, no.15, pp.4068 - 4070, 2006-08

25
The effect of HS-111, a novel thiazolamine derivative, on apoptosis and angiogenesis of hepatocellular carcinoma cells

Choi, Myung-Joo; Lee, Hyunseung; Lee, Ju-Hee; Jung, Kyung Hee; Kim, Donghee; Hong, Sungwoo; Hong, Soon-Sun, ARCHIVES OF PHARMACAL RESEARCH, v.35, no.4, pp.747 - 754, 2012-03

26
Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton's Tyrosine Kinase

Kim, Taeho; Kim, Kewon; Park, Inyoung; Hong, Sungwoo; Park, Hwangseo, JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.62, no.18, pp.4500 - 4511, 2022-09

27
Virtual screening and biochemical evaluation to identify new inhibitors of mammalian target of rapamycin (mTOR)

Park, Hwangseo; Choe, Hyeonjeong; Hong, Sungwoo, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.24, no.3, pp.835 - 838, 2014-02

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