Browse "Dept. of Chemistry(화학과)" by Subject MUTATIONS

Showing results 1 to 26 of 26

1
A novel imidazopyridine analogue as a phosphatidylinositol 3-kinase inhibitor against human breast cancer

Lee, Hyunseung; Li, Guang-Yong; Jeong, Yujeong; Jung, Kyung Hee; Lee, Ju-Hee; Ham, Kyungrok; Hong, Sungwoo; et al, CANCER LETTERS, v.318, no.1, pp.68 - 75, 2012-05

2
A novel imidazopyridine derivative, HS-106, induces apoptosis of breast cancer cells and represses angiogenesis by targeting the PI3K/mTOR pathway

Li, Guang-Yong; Jung, Kyung Hee; Lee, Hyunseung; Son, Mi Kwon; Seo, JuHyeon; Hong, Sang-Won; Jeong, Yujeong; et al, CANCER LETTERS, v.329, no.1, pp.59 - 67, 2013-02

3
A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells

Lee, Hyunseung; Kim, Soo Jung; Jung, Kyung Hee; Son, Mi Kwon; Yan, Hong Hua; Hong, Sungwoo; Hong, Soon-Sun, ONCOLOGY REPORTS, v.30, no.2, pp.863 - 869, 2013-08

4
Design and Synthesis of Imidazopyridine Analogues as Inhibitors of Phosphoinositide 3-Kinase Signaling and Angiogenesis

Kim, O; Jeong, Y; Lee, H; Hong, SS; Hong, Sungwoo, JOURNAL OF MEDICINAL CHEMISTRY, v.54, no.7, pp.2455 - 2466, 2011-04

5
Detection of Single Nucleotide Polymorphisms by a Gold Nanowire-on-Film SERS Sensor Coupled with S1 Nuclease Treatment

Yoo, Seung Min; Kang, Taejoon; Kim, Bongsoo; Lee, SangYup, CHEMISTRY-A EUROPEAN JOURNAL, v.17, no.31, pp.8657 - 8662, 2011-07

6
Direct, sequence-specific detection of dsDNA based on peptide nucleic acid and graphene oxide without requiring denaturation

Lee, Jieon; Park, Il-Soo; Jung, Euihan; Lee, Younghoon; Min, Dal-Hee, BIOSENSORS & BIOELECTRONICS, v.62, pp.140 - 144, 2014-12

7
Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products

Park, Hwangseo; Lee, Soyoung; Hong, Sungwoo, JOURNAL OF NATURAL PRODUCTS, v.79, no.2, pp.293 - 299, 2016-02

8
Discovery of Low Micromolar Dual Inhibitors for Wild Type and L1196M Mutant of Anaplastic Lymphoma Kinase through Structure-Based Virtual Screening

Shin, Saemina; Mah, Shinmee; Hong, Sungwoo; Park, Hwangseo, JOURNAL OF CHEMICAL INFORMATION AND MODELING, v.56, no.4, pp.802 - 810, 2016-04

9
Discovery of new aminopyrimidine-based phosphoinositide 3-kinase beta (PI3K beta) inhibitors with selectivity over PI3K alpha

Kim, J; Hong, S; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.21, no.23, pp.6977 - 6981, 2011-12

10
Discovery of new azaindole-based PI3K alpha inhibitors: Apoptotic and antiangiogenic effect on cancer cells

Hong, S; Lee, S; Kim, B; Lee, H; Hong, SS; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.20, no.24, pp.7212 - 7215, 2010-12

11
Elution-free DNA detection using CRISPR/Cas9-mediated light-up aptamer transcription: Toward all-in-one DNA purification and detection tube

Song, Jayeon; Song, Younseong; Jang, Hyowon; Moon, Jeong; Kang, Hyunju; Huh, Yong-Min; Son, Hye Young; et al, BIOSENSORS & BIOELECTRONICS, v.225, 2023-04

12
Fluorescence Imaging of Mitochondrial DNA Base Excision Repair Reveals Dynamics of Oxidative Stress Responses

Jun, Yong Woong; Albarran, Eddy; Wilson, David L.; Ding, Jun; Kool, Eric T., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.61, no.6, 2022-02

13
Fluorescent phosphoinositide 3-kinase inhibitors suitable for monitoring of intracellular distribution

Kim, D; Lee, H; Jun, H; Hong, SS; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY, v.19, no.8, pp.2508 - 2516, 2011-04

14
Identification of beta-Lapachone Analogs as Novel MALT1 Inhibitors To Treat an Aggressive Subtype of Diffuse Large B-Cell Lymphoma

Lim, Sang Min; Jeong, Yujeong; Lee, Suhyun; Im, Honggu; Tae, Hyun Seop; Kim, Byung Gyu; Park, Hee Dong; et al, JOURNAL OF MEDICINAL CHEMISTRY, v.58, no.21, pp.8491 - 8502, 2015-11

15
Identification of common inhibitors of wild-type and T315I mutant of BCR-ABL through the parallel structure-based virtual screening

Park, Hwangseo; Hong, Seunghee; Hong, Sungwoo, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, v.26, no.8, pp.983 - 992, 2012-08

16
Identification of novel BRAF kinase inhibitors with structure-based virtual screening

Park, H; Choi, H; Hong, S; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.21, no.19, pp.5753 - 5756, 2011-10

17
Recognition of Single Mismatched DNA Using MutS-Immobilized Carbon Nanotube Field Effect Transistor Devices

Kim, Suphil; Kim, Tae Gyun; Byon, Hye Ryung; Shin, Hyun Joon; Ban, Changill; Choi, Hee Cheul, JOURNAL OF PHYSICAL CHEMISTRY B, v.113, no.36, pp.12164 - 12168, 2009-09

18
Rho-dependent Termination of ssrS (6S RNA) Transcription in Escherichia coli IMPLICATION FOR 3 PROCESSING OF 6S RNA AND EXPRESSION OF DOWNSTREAM ygfA (PUTATIVE 5-FORMYL-TETRAHYDROFOLATE CYCLO-LIGASE)

Chae, Hui-Seok; Han, Kook; Kim, Kwang-sun; Park, Hong-Marn; Lee, Jung-Min; Lee, Younghoon, JOURNAL OF BIOLOGICAL CHEMISTRY, v.286, no.1, pp.114 - 122, 2011-01

19
Selectivity Enhancement Arising from Interactions at the PI3K Unique Pocket

Jeong, Yujeong; Lee, Junghyun; Lee, Yoonji; Ham, Kyungrok; Choi, Sun; Hong, Sungwoo, CHEMMEDCHEM, v.7, no.8, pp.1379 - 1383, 2012-08

20
Small Substrate or Large? Debate Over the Mechanism of Glycation Adduct Repair by DJ-1

Jun, Yong Woong; Kool, Eric T., CELL CHEMICAL BIOLOGY, v.27, no.9, pp.1117 - 1123, 2020-09

21
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16(INK4a)

Russo, AA; Tong, L; Lee, Jie-Oh; Jeffrey, PD; Pavletich, NP, NATURE, v.395, no.6699, pp.237 - 243, 1998-09

22
Structure of a DNA duplex containing a site-specific Dewar isomer: Structural influence of the 3 -T center dot G base pair of the Dewar product.

Lee, JH; Choi, Byong-Seok, JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, v.33, no.3, pp.268 - 275, 2000-05

23
Structure-based de novo design and biochemical evaluation of novel BRAF kinase inhibitors

Park, Hwangseo; Jeong, Yujeong; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.22, no.2, pp.1027 - 1030, 2012-01

24
Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S Mutant of Leucine-Rich Repeat Kinase 2

Park, Hwangseo; Kim, Taeho; Kim, Kewon; Jang, Ahyoung; Hong, Sungwoo, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.21, pp.12825, 2022-11

25
Structure-based virtual screening approach to the discovery of phosphoinositide 3-kinase alpha inhibitors

Park, H; Choi, H; Hong, S; Kim, D; Oh, DS; Hong, Sungwoo, BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.21, no.7, pp.2021 - 2024, 2011-04

26
Suppression of tumor proliferation and angiogenesis of hepatocellular carcinoma by HS-104, a novel phosphoinositide 3-kinase inhibitor

Jung, Kyung Hee; Zheng, Hong-Mei; Jeong, Yujeong; Choi, Myung-Joo; Lee, Hyunseung; Hong, Sang-Won; Lee, Hee-Seung; et al, CANCER LETTERS, v.328, no.1, pp.176 - 187, 2013-01

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