Browse "Dept. of Chemistry(화학과)" by Author Ramamoorthy, Ayyalusamy
Showing results 1 to 23 of 23
| A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms Derrick, Jeffrey S.; Kerr, Richard A.; Nam, Younwoo; Oh, Shin Bi; Lee, Hyuck Jin; Earnest, Kaylin G.; Suh, Nayoung; et al, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.137, no.46, pp.14785 - 14797, 2015-11 |
| A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-beta implicated in Alzheimer's disease Savelieff, Masha G.; Liu, Yuzhong; Senthamarai, Russell R. P.; Korshavn, Kyle J.; Lee, Hyuck Jin; Ramamoorthy, Ayyalusamy; Lim, Mi Hee, CHEMICAL COMMUNICATIONS, v.50, no.40, pp.5301 - 5303, 2014-05 |
| Amyloid-beta adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation Korshavn, Kyle J.; Bhunia, Anirban; Lim, Mi Hee; Ramamoorthy, Ayyalusamy, CHEMICAL COMMUNICATIONS, v.52, no.5, pp.882 - 885, 2016-01 |
| An Iridium(III) Complex as a Photoactivatable Tool for Oxidation of Amyloidogenic Peptides with Subsequent Modulation of Peptide Aggregation Kang, Juhye; Lee, Shin Jung C.; Nam, Jung Seung; Lee, Hyuck Jin; Kang, Myeong-Gyun; Korshavn, Kyle J.; Kim, Hyun-Tak; et al, CHEMISTRY-A EUROPEAN JOURNAL, v.23, no.7, pp.1645 - 1653, 2017-01 |
| Biophysical insights into the membrane interaction of the core amyloid-forming A beta(40) fragment K16-K28 and its role in the pathogenesis of Alzheimer's disease Bera, Swapna; Korshavn, Kyle J.; Kar, Rajiv K.; Lim, Mi Hee; Ramamoorthy, Ayyalusamy; Bhunia, Anirban, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, v.18, no.25, pp.16890 - 16901, 2016-07 |
| Design of small molecules that target metal-A beta species and regulate metal-induced A beta aggregation and neurotoxicity Choi, Jung-Suk; Braymer, Joseph J.; Nanga, Ravi P. R.; Ramamoorthy, Ayyalusamy; Lim, Mi Hee, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.107, no.51, pp.21990 - 21995, 2010-12 |
| Development of Bifunctional Stilbene Derivatives for Targeting and Modulating Metal-Amyloid-beta Species Braymer, Joseph J.; Choi, Jung-Suk; DeToma, Alaina S.; Wang, Chen; Nam, Kisoo; Kampf, Jeffrey W.; Ramamoorthy, Ayyalusamy; et al, INORGANIC CHEMISTRY, v.50, no.21, pp.10724 - 10734, 2011-11 |
| Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-beta (1-40) Lin, Yuxi; Sahoo, Bikash R.; Ozawa, Daisaku; Kinoshita, Misaki; Kang, Juhye; Lim, Mi Hee; Okumura, Masaki; et al, ACS NANO, v.13, no.8, pp.8766 - 8783, 2019-08 |
| Dual-function triazole-pyridine derivatives as inhibitors of metal-induced amyloid-beta aggregation Jones, Michael R.; Service, Erin L.; Thompson, John R.; Wang, Michael C. P.; Kimsey, Isaac J.; DeToma, Alaina S.; Ramamoorthy, Ayyalusamy; et al, METALLOMICS, v.4, no.9, pp.910 - 920, 2012-08 |
| Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-beta aggregation Lee, Hyuck Jin; Kerr, Richard A.; Korshavn, Kyle J.; Lee, Jeeyeon; Kang, Juhye; Ramamoorthy, Ayyalusamy; Ruotolo, Brandon T.; et al, INORGANIC CHEMISTRY FRONTIERS, v.3, no.3, pp.381 - 392, 2016-03 |
| Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-beta, and Oxidative Stress in Alzheimer's Disease Derrick, Jeffrey S.; Kerr, Richard A.; Korshavn, Kyle J.; McLane, Michael J.; Kang, Juhye; Nam, Eunju; Ramamoorthy, Ayyalusamy; et al, INORGANIC CHEMISTRY, v.55, no.10, pp.5000 - 5013, 2016-05 |
| Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-beta species Hyung, Suk-Joon; DeToma, Alaina S.; Brender, Jeffrey R.; Lee, Sanghyun; Vivekanandan, Subramanian; Kochi, Akiko; Choi, Jung-Suk; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.110, no.10, pp.3743 - 3748, 2013-03 |
| Interaction and reactivity of synthetic aminoisoflavones with metal-free and metal-associated amyloid-beta DeToma, Alaina S.; Krishnamoorthy, Janarthanan; Nam, Younwoo; Lee, Hyuck Jin; Brender, Jeffrey R.; Kochi, Akiko; Lee, Dongkuk; et al, CHEMICAL SCIENCE, v.5, no.12, pp.4851 - 4862, 2014-12 |
| Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease Beck, Michael W.; Derrick, Jeffrey S.; Suh, Jong-Min; Kim, Mingeun; Korshavn, Kyle J.; Kerr, Richard A.; Cho, Woo Jong; et al, CHEMMEDCHEM, v.12, no.22, pp.1828 - 1838, 2017-11 |
| Misfolded proteins in Alzheimer's disease and type II diabetes DeToma, Alaina S.; Salamekh, Samer; Ramamoorthy, Ayyalusamy; Lim, Mi Hee, CHEMICAL SOCIETY REVIEWS, v.41, no.2, pp.608 - 621, 2012-01 |
| Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease Jones, Michael R.; Mathieu, Emilie; Dyrager, Christine; Faissner, Simon; Vaillancourt, Zavier; Korshavn, Kyle J.; Lim, Mi Hee; et al, CHEMICAL SCIENCE, v.8, no.8, pp.5636 - 5643, 2017-08 |
| Multifunctional quinoline-triazole derivatives as potential modulators of amyloid-beta peptide aggregation Jones, Michael R.; Dyrager, Christine; Hoarau, Marie; Korshavn, Kyle J.; Lim, Mi Hee; Ramamoorthy, Ayyalusamy; Storr, Tim, JOURNAL OF INORGANIC BIOCHEMISTRY, v.158, pp.131 - 138, 2016-05 |
| Rational Design of a Structural Framework with Potential Use to Develop Chemical Reagents That Target and Modulate Multiple Facets of Alzheimer's Disease Lee, Sanghyun; Zheng, Xueyun; Krishnamoorthy, Janarthanan; Savelieff, Masha G.; Park, Hyun Min; Brender, Jeffrey R.; Kim, Jin Hoon; et al, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.136, no.1, pp.299 - 310, 2014-01 |
| Reactivity of Metal-Free and Metal-Associated Amyloid-beta with Glycosylated Polyphenols and Their Esterified Derivatives Korshavn, Kyle J.; Jang, Milim; Kwak, Yeon Ju; Kochi, Akiko; Vertuani, Silvia; Bhunia, Anirban; Manfredini, Stefano; et al, SCIENTIFIC REPORTS, v.5, 2015-12 |
| Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid- beta Korshavn, Kyle J.; Satriano, Cristina; Lin, Yuxi; Zhang, Rongchun; Dulchavsky, Mark; Bhunia, Anirban; Ivanova, Magdalena I.; et al, JOURNAL OF BIOLOGICAL CHEMISTRY, v.292, no.11, pp.4638 - 4650, 2017-03 |
| Small Molecule Modulators of Copper-Induced A beta Aggregation Hindo, Sarmad S.; Mancino, Allana M.; Braymer, Joseph J.; Liu, Yihong; Vivekanandan, Subramanian; Ramamoorthy, Ayyalusamy; Lim, Mi Hee, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.131, no.46, pp.16663 - 16665, 2009-11 |
| Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease Lee, Hyuck Jin; Korshavn, Kyle J.; Nam, Younwoo; Kang, Juhye; Paul, Thomas J.; Kerr, Richard A.; Youn, Il Seung; et al, CHEMISTRY-A EUROPEAN JOURNAL, v.23, no.11, pp.2706 - 2715, 2017-02 |
| Structural Characterization and Inhibition of Toxic Amyloid-beta Oligomeric Intermediates Ramamoorthy, Ayyalusamy; Lim, Mi Hee, BIOPHYSICAL JOURNAL, v.105, no.2, pp.287 - 288, 2013-07 |
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