Browse "College of Life Science and Bioengineering(생명과학기술대학)" by Subject HAMSTER OVARY CELLS
Showing results 1 to 58 of 58
A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner Oh, Nuri; Kim, Kangsan; Kim, Soo Jin; Park, Intae; Lee, Jung-Eun; Seo, Young Suk; An, Hyun Joo; et al, SCIENTIFIC REPORTS, v.5, 2015-10 |
| A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis Kim, Hak-Zoo; Jung, Keehoon; Kim, Ho Min; Cheng, Yifan; Koh, Gou Young, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, v.1793, no.5, pp.772 - 780, 2009-05 |
| Anti-cell death engineering of CHO cells: Co-overexpression of Bcl-2 for apoptosis inhibition, Beclin-1 for autophagy induction Lee, Jae-Seong; Ha, Tae-Kwang; Park, Jin-Hyoung; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.110, no.8, pp.2195 - 2207, 2013-08 |
| Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity Ha, Tae Kwang; Hansen, Anders Holmgaard; Kol, Stefan; Kildegaard, Helene Faustrup; Lee, Gyun Min, Biotechnology Journal, v.13, no.3, 2018-03 |
| Bcl-2 overexpression in CHO cells improves polyethylenimine-mediated gene transfection Lee, So-Jeong; Lee, Gyun-Min, PROCESS BIOCHEMISTRY, v.48, no.9, pp.1436 - 1440, 2013-09 |
| Bcl-xL Overexpression does not Enhance Specific Erythropoietin Productivity of Recombinant CHO Cells Grown at 33 degrees C and 37 degrees C Kim, Yeon-Gu; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.25, no.1, pp.252 - 256, 2009-01 |
| Calnexin overexpression sensitizes recombinant CHO cells to apoptosis induced by sodium butyrate treatment Mohan, Chaya; Lee, Gyun-Min, CELL STRESS & CHAPERONES, v.14, no.1, pp.49 - 60, 2009-01 |
| Case study on human alpha 1-antitrypsin: Recombinant protein titers obtained by commercial ELISA kits are inaccurate Hansen, Henning Gram; Kildegaard, Helene Faustrup; Lee, Gyun Min; Kol, Stefan, BIOTECHNOLOGY JOURNAL, v.11, no.12, pp.1648 - 1656, 2016-12 |
| Characterization and Expression of Proprotein Convertases in CHO Cells: Efficient Proteolytic Maturation of Human Bone Morphogenetic Protein-7 Sathya Murthy, Madhavi; Kim, Che Lin; Bang, You Lim; Kim, Young Sik; Jang, Ju Woong; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.112, no.3, pp.560 - 568, 2015-03 |
| Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure Kim, SJ; Kim, NS; Ryu, CJ; Hong, HJ; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.58, no.1, pp.73 - 84, 1998-04 |
| Characterization of humanized antibody produced by apoptosis-resistant CHO cells under sodium butyrate-induced condition Kim, NS; Chang, KH; Chung, BS; Kim, SH; Kim, Jung Hoe; Lee, Gyun-Min, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.13, pp.926 - 936, 2003-12 |
| Characterization of site-specific recombination mediated by Cre recombinase during the development of erythropoietin producing CHO cell lines Kim, Min-Soo; Kim, Won-Hee; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.13, no.4, pp.418 - 423, 2008-07 |
| Chemical Inhibition of Autophagy: Examining Its Potential to Increase the Specific Productivity of Recombinant CHO Cell Lines Baek, Eric H; Kim, Che Lin; Kim, Mi Gyeom; Lee, Jae Seong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.113, no.9, pp.1953 - 1961, 2016-09 |
| Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells Lee, Joohyoung; Park, Jong-Ho; Park, Sun-Hye; Kim, Sun-Hong; Kim, Jee-Yon; Min, Jeong-Ki; Lee, Gyun Min; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.102, no.11, pp.4729 - 4739, 2018-06 |
| Combinatorial treatment with lithium chloride enhances recombinant antibody production in transiently transfected CHO and HEK293E cells Kim, Che Lin; Ha, Tae Kwang; Lee, Gyun Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.5, pp.667 - 675, 2016-09 |
| Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells Shin, Seunghyeon; Kim, Su Hyun; Shin, Sung Wook; Grav, Lise Marie; Pedersen, Lasse Ebdrup; Lee, Jae Seong; Lee, Gyun Min, ACS SYNTHETIC BIOLOGY, v.9, no.6, pp.1263 - 1269, 2020-06 |
| Comprehensive characterization of dihydrofolate reductase-mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies Lee, Sang Yoon; Baek, Minhye; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.16, no.5, 2021-05 |
| Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies Noh, Soo Min; Shin, Seunghyeon; Lee, Gyun Min, SCIENTIFIC REPORTS, v.8, no.5361, pp.1 - 11, 2018-03 |
| Current state and perspectives on erythropoietin production Lee, Jae-Seong; Ha, Tae-Kwang; Lee, Seung-Joo; Lee, Gyun-Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.95, no.6, pp.1405 - 1416, 2012-09 |
| Development of an in vitro screening system for synthetic signal peptide in mammalian cell-based protein production Park, Jong-Ho; Lee, Hoon-Min; Jin, Eun-Ju; Lee, Eun-Ji; Kang, Yeon-Ju; Kim, Sungkyun; Yoo, Sung-Sick; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.106, no.9-10, pp.3571 - 3582, 2022-05 |
| Development of apoptosis-resistant CHO cell line expressing PyLT for the enhancement of transient antibody production Kim, Won-Hee; Kim, Min-Soo; Kim, Yeon-Gu; Lee, Gyun-Min, PROCESS BIOCHEMISTRY, v.47, no.12, pp.2557 - 2561, 2012-12 |
| Development of serum-free medium supplemented with hydrolysates for the production of therapeutic antibodies in CHO cell cultures using design of experiments Kim, Sung Hyun; Lee, Gyun-Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.83, no.4, pp.639 - 648, 2009-06 |
| Differential in-gel electrophoresis (DIGE) analysis of CHO cells under hyperosmotic pressure: Osmoprotective effect of glycine betaine addition Kim, Jee Yon; Kim, Yeon-Gu; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.109, no.6, pp.1395 - 1403, 2012-06 |
| Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment Lee, Jae-Seong; Kim, Yeon-Jung; Kim, Che-Lin; Lee, Gyun-Min, JOURNAL OF BIOTECHNOLOGY, v.161, no.1, pp.34 - 41, 2012-09 |
| Effect of culture pH on recombinant antibody production by a new human cell line, F2N78, grown in suspension at 33.0 A degrees C and 37.0 A degrees C Seo, Jin-Seok; Kim, Yeon-Jung; Cho, Jong-Moon; Baek, Eric; Lee, Gyun-Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.97, no.12, pp.5283 - 5291, 2013-06 |
| Effect of doxycycline-regulated ERp57 expression on specific thrombopoietin productivity of recombinant CHO cells Hwang, SO; Chung, JY; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.19, pp.179 - 184, 2003-01 |
| Effect of doxycycline-regulated protein disulfide isomerase expression on the specific productivity of recombinant CHO cells: Thrombopoietin and antibody Mohan, Chaya; Park, Soon Hye; Chung, Joo Young; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.98, no.3, pp.611 - 615, 2007-10 |
| Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture Seo, Jin Seok; Min, Byung Sup; Kim, Yeon Jung; Cho, Jong Moon; Baek, Eric H; Cho, Myung Sam; Lee, Gyun-Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.98, no.8, pp.3509 - 3515, 2014-04 |
| Effect of Mild-Thiol Reducing Agents and alpha 2,3-Sialyltransferase Expression on Secretion and Sialylation of Recombinant EPO in CHO Cells Chang, Kern Hee; Jeong, Yeon Tae; Kwak, Chan Yeong; Choi, One; Kim, Jung Hoe, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.23, no.5, pp.699 - 706, 2013-05 |
| Effect of Sodium Butyrate on glycosylation of recombinant Erythropoietin Chung, BS; Jeong, YT; Chang, KH; Kim, JS; Kim, Jung Hoe, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.11, no.6, pp.1087 - 1092, 2001-12 |
| Effects of cloned gene dosage on the response of recombinant CHO cells to hyperosmotic pressure in regard to cell growth and antibody production Ryu, J.S.; Lee, M.S.; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.17, no.6, pp.993 - 999, 2001-11 |
| Effects of culture temperature and pH on flag-tagged COMP angiopoietin-1 (FCA1) production from recombinant CHO cells: FCA1 aggregation Hwang, Su-Jeong; Yoon, Sung-Kwan; Koh, Gou-Young; Lee, Gyun-Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.91, no.2, pp.305 - 315, 2011-07 |
| Enhanced human thrombopoietin production by sodium butyrate addition to serum-free suspension culture of Bcl-2-overexpressing CHO cells Sung, YH; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.21, pp.50 - 57, 2005-01 |
| Enhanced Interferon-beta Production by CHO Cells Through Elevated Osmolality and Reduced Culture Temperature Han, Young-Kue; Koo, Tai-Young; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.25, no.5, pp.1440 - 1447, 2009-09 |
| Enhanced Sialylation of Recombinant Erythropoietin in CHO Cells by Human Glycosyltransferase Expression Yeon Tae Jeong; One Choi; Hye Rim Lim; Young Dok Son; Hong Jin Kim; Kim, Jung Hoe, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.18, pp.1945 - 1952, 2008-12 |
| Enhancement of Recombinant Antibody Production in HEK 293E Cells by WPRE Kim, Keun-Soo; Kim, Min Soo; Moon, Ji Hyun; Jeong, Moon Sik; Kim, Jinhong; Lee, Gyun-Min; Myung, Pyung-Keun; et al, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.14, no.5, pp.633 - 638, 2009-10 |
| Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis Kwak, Chan-Yeong; Park, Seung-Yeol; Lee, Chung Geun; Okino, Nozomu; Ito, Makoto; Kim, Jung Hoe, SCIENTIFIC REPORTS, v.7, 2017-10 |
| Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells Hong, Jong Kwang; Lee, Gyun-Min; Yoon, Sung Kwan, JOURNAL OF BIOTECHNOLOGY, v.155, no.2, pp.225 - 231, 2011-09 |
| High productivity of t-PA in CHO cells using hypoxia response element Bae, GW; Jeong, DW; Kim, HJ; Lee, Gyun-Min; Park, H; Choe, TB; Kang, S; et al, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.16, pp.695 - 703, 2006-05 |
| Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines Kim, Che Lin; Lee, Gyun Min, METABOLIC ENGINEERING, v.52, pp.57 - 67, 2019-03 |
| Improving the secretory capacity of CHO producer cells: The effect of controlled Blimp1 expression, a master transcription factor for plasma cells Kim, Su Hyun; Baek, Minhye; Park, Sungje; Shin, Seunghyeon; Lee, Jae Seong; Lee, Gyun Min, METABOLIC ENGINEERING, v.69, pp.73 - 86, 2022-01 |
| Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells Lee, Chung Geun; Oh, Myung Jin; Park, Seung-Yeol; An, Hyun Joo; Kim, Jung Hoe, SCIENTIFIC REPORTS, v.8, 2018-05 |
| Initial transcriptome and proteome analyses of low culture temperature-induced expression in CHO cells producing erythropoietin Baik, JY; Lee, MS; An, SR; Yoon, SK; Joo, EJ; Kim, YH; Park, HW; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.93, pp.361 - 371, 2006-02 |
| Intracellular responses of antibody-producing H69K-NGD transfectoma subjected to hyperosmotic pressure Bae, SW; Lee, Gyun-Min, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.15, pp.579 - 586, 2005-06 |
| Key determinants in the occurrence of clonal variation in humanized antibody expression of CHO cells during dihydrofolate reductase mediated gene amplification Kim, NS; Byun, TH; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.17, no.1, pp.69 - 75, 2001 |
| Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation Grav, Lise Marie; Sergeeva, Dania; Lee, Jae Seong; de Mas, Igor Marin; Lewis, Nathan E.; Andersen, Mikael Rordam; Nielsen, Lars Keld; et al, ACS SYNTHETIC BIOLOGY, v.7, no.9, pp.2148 - 2159, 2018-09 |
| Mitigating Clonal Variation in Recombinant Mammalian Cell Lines Lee, Jae Seong; Kildegaard, Helene Faustrup; Lewis, Nathan E.; Lee, Gyun Min, TRENDS IN BIOTECHNOLOGY, v.37, no.9, pp.931 - 942, 2019-09 |
| Protein reference mapping of dihydrofolate reductase-deficient CHO DG44 cell lines using 2-dimensional electrophoresis Lee, Jae-Seong; Park, Hyun-Ju; Kim, Young-Hwan; Lee, Gyun-Min, PROTEOMICS, v.10, pp.2292 - 2302, 2010-06 |
| Rapamycin treatment inhibits CHO cell death in a serum-free suspension culture by autophagy induction Lee, Jae-Seong; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.109, no.12, pp.3093 - 3102, 2012-12 |
| Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress Shin, Seunghyeon; Kim, Su Hyun; Park, Jong-Ho; Lee, Jae Seong; Lee, Gyun Min, METABOLIC ENGINEERING, v.72, pp.247 - 258, 2022-07 |
| Reduction of ammonia and lactate through the coupling of glutamine synthetase selection and downregulation of lactate dehydrogenase-A in CHO cells Noh, Soo Min; Park, Jin-Hyoung; Lim, Myung Sin; Kim, Jong Won; Lee, Gyun Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.101, no.3, pp.1035 - 1045, 2017-02 |
| Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing Jae Seong Lee; Park, Jin-Hyoung; Ha, Tae Kwang; Samoudi, Mojtaba; Lewis, Nathan E.; Palsson, Bernhard O.; Kildegaard, Helene Faustrup; et al, ACS SYNTHETIC BIOLOGY, v.7, no.12, pp.2867 - 2878, 2018-12 |
| Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion Kallehauge, Thomas Beuchert; Li, Shangzhong; Pedersen, Lasse Ebdrup; Ha, Tae Kwang; Ley, Daniel; Andersen, Mikael Rordam; Kildegaard, Helene Faustrup; et al, SCIENTIFIC REPORTS, v.7, pp.1 - 10, 2017-01 |
| Small molecule epigenetic modulators for enhancing recombinant antibody production in CHO cell cultures Kim, Dongil; Yoon, Chansik; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.119, no.3, pp.820 - 831, 2022-03 |
| Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering Pristovsek, Nusa; Nallapareddy, Saranya; Grav, Lise Marie; Hefzi, Hooman; Lewis, Nathan E.; Rugbjerg, Peter; Hansen, Henning Gram; et al, ACS SYNTHETIC BIOLOGY, v.8, no.4, pp.758 - 774, 2019-04 |
| Targeted Gene Deletion Using DNA-Free RNA-Guided Cas9 Nuclease Accelerates Adaptation of CHO Cells to Suspension Culture Lee, namil; Shin, Jongoh; Park, Jin-Hyoung; Lee, Gyun Min; Suhyung Cho; Cho, Byung-Kwan, ACS SYNTHETIC BIOLOGY, v.5, no.11, pp.1211 - 1219, 2016-11 |
| The molecular weight and concentration of dextran sulfate affect cell growth and antibody production in CHO cell cultures Park, Jin-Hyoung; Lim, Myung Sin; Woo, Ju Rang; Kim, Jong Won; Lee, Gyun Min, BIOTECHNOLOGY PROGRESS, v.32, no.5, pp.1113 - 1122, 2016-09 |
| Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity Park, Jin-Hyoung; Noh, Soo Min; Woo, Ju Rang; Kim, Jong Won; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.11, no.4, pp.487 - 496, 2016-04 |
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