Synthesis of 2-[4,5]-benzo-2-thiono-2-mercapto-1,3,2-oxazaphospholano-2',4',5'-trichloroacetanilide derivatives

Abstract

Ortho-aminophenol derivatives reacted in pyridine with phosphorus pentasulfide to give (4,5)-benzo-2-thiono-2-mercapto-1,3,2-oxazaphospholane S-pyridinium salt derivatives in good yields (80-90%). 2-chloro-2``,4``,5``-trichloroacetanilide was prepared by reaction of 2,4,5-trichloroaniline with chloroacetyl-chloride at low temperature. 2- (4,5)-benzo-2-thiono-2-mercapto-1,3,2-oxazaphospholano-2``,4``,5``,- trichloroacetanilide derivatives that we expect they will be exhibited antibacterial and antifungal action for phythopathogenic fungi was synthesized by reaction of (4,5)-benzo-2-thiono-2-mercapto-1,3,2-oxazaphospholane S-pyridinium salt derivatives with 2-chloro-2``,4``,5``-trichloroacetanilide at 45-60℃