DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Jhon, Mu-Shik | - |
dc.contributor.advisor | 전무식 | - |
dc.contributor.author | Moon, Myung-Jun | - |
dc.contributor.author | 문명준 | - |
dc.date.accessioned | 2011-12-13T04:55:14Z | - |
dc.date.available | 2011-12-13T04:55:14Z | - |
dc.date.issued | 1983 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=63602&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/32352 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 화학과, 1983.2, [ [iii], 47 p. ] | - |
dc.description.abstract | To understand the important role of Y-base adjacent to the anticodon stabilizing codon-anticodon interaction, a study has been undertaken for the model compound involving the interaction between Y-base and anticodon as well as the participation of water molecules by calculating the conformational free energy using an empirical potential function. We restrict our analysis to sites directly associated with Y-base by varying only the backbone torsion angles of Y-base. The hydration and $Mg^{+2}$ binding effects on the conformational stability of Y-base are calculated and discussed. The nonhydrated Y-base is proved to be less stable than the hydrated one. The free energy change due to the hydration of Y-base amounts to -119.5 kcal/mole, in which the conformational energy change is -142.4 kcal/mole and the configurational entropy change is -76.9 e.u.. Contributions of the water molecules bound to Y-base and $Mg^{+2}$ are the major factors in the total interaction energy of Y-base. | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.title | Conformational study of Y-base in yeast $tRNA^{phe}$ | - |
dc.title.alternative | 효모 페닐알라닌 전달리보핵산에 있는 Y 염기의 구조적 연구 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 63602/325007 | - |
dc.description.department | 한국과학기술원 : 화학과, | - |
dc.identifier.uid | 000811092 | - |
dc.contributor.localauthor | Jhon, Mu-Shik | - |
dc.contributor.localauthor | 전무식 | - |
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