This study multifunctional wearable bioelectronics (MWBs) integrated with a piezoelectric sensor and a micropatterned temperature sensor for accurate detection of human physiological signals. Piezoelectric nanocomposite uniformity, stretchability, and adhesion is improved through the functionalization of nanoparticles with glycidyl silane and nonionic surfactants dispersion in the organic polymer matrix. Additionally, crack-free nanometal layers are deposited on the nanocomposite interface with high adhesion by thiol silane functionalization and oxygen plasma treatment. The MWBs exhibit a temperature sensitivity of 7.1 omega degrees C-1 (R2 of 0.999) between 30 degrees C to 40 degrees C, a pressure sensitivity of 72 mV kPa-1 (R2 of 0.998) within 0.5 kPa to 10 kPa, and a stable mechanical durability. MWBs have demonstrated to detect subtle pulse waveforms at an arm-mimicking phantom and human skin, respectively. Furthermore, MWBs are applied to analyze physiological signal characteristics caused by human stress, demonstrating its potential for use in healthcare electronics in various medical applications. Multifunctional wearable bioelectronics (MWBs) are demonstrated with integrated a piezoelectric pulse wave sensor and a temperature sensor for physiological signal detection by enhancing nanocomposite dispersion and metal deposition. The MWBs exhibit high sensitivity and resolution in detecting blood pulse waveforms and skin temperature changes, demonstrating its potential for mental stress analysis.image