DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Kim, Yong-Hae | - |
dc.contributor.advisor | 김용해 | - |
dc.contributor.author | Jung, Sun-Ho | - |
dc.contributor.author | 정선호 | - |
dc.date.accessioned | 2011-12-13T04:54:25Z | - |
dc.date.available | 2011-12-13T04:54:25Z | - |
dc.date.issued | 1981 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=62879&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/32296 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 화학과, 1981.2, [ [iii], 45 p. ] | - |
dc.description.abstract | A new method to synthesize $\alpha$-oximino-$\alpha$-haloketones using alkyl thionitrites was developed under mild conditions. The reactions of $\alpha$-haloketones with t-butyl thionitrite or n-butyl thionitrite in anhydrous ether containing gaseous hydrogen chloride under mild conditions ($25-35^\circ C$) afforded the corresponding oximes. In the case of using more stable t-butyl thionitrite, the better yields of oximes were obtained than using n-butyl thionitrite probably due to the instability of n-butyl thionitrite. Since the sulfurnitrogen bond of thionitrites is relatively weaker than the oxygen-nitrogen bond of nitrites and also $RS^-$ is better leaving group than $RO^-$ in the nitrosation step, thionitrites are considered to be better reagents than nitrites for the nitrosation of $\alpha$-haloketones. Undoubtedly, this reaction appears to be initiated by nitrosation on the carbon attached to halogen of $\alpha$-haloketones. Alkyl or benzyl chloromethyl ketones reacted with t-butyl thionitrite to give the corresponding oximes in good yields (80-95\%). While, in the case of aryl halomethyl ketones, the yields of oximes were low (10-40\%). | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.title | New synthesis of α-halo-α-oximinoketones by the reactions of α-haloketones with thionitrites | - |
dc.title.alternative | 티오 나이트 라이트와 α-할로케톤의 반응에 의한 α-옥시미노-α-할로케톤의 새로운 합성 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 62879/325007 | - |
dc.description.department | 한국과학기술원 : 화학과, | - |
dc.identifier.uid | 000791239 | - |
dc.contributor.localauthor | Kim, Yong-Hae | - |
dc.contributor.localauthor | 김용해 | - |
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