DC Field | Value | Language |
---|---|---|
dc.contributor.author | Duong, Quynh Huong | ko |
dc.contributor.author | Kwahk, Eunjeong | ko |
dc.contributor.author | Kim, Jumi | ko |
dc.contributor.author | Park, Hahyoun | ko |
dc.contributor.author | Cho, Heyjin | ko |
dc.contributor.author | Kim, Hyunwoo | ko |
dc.date.accessioned | 2024-09-02T11:00:10Z | - |
dc.date.available | 2024-09-02T11:00:10Z | - |
dc.date.created | 2024-08-29 | - |
dc.date.issued | 2024-01 | - |
dc.identifier.citation | ANALYTICAL CHEMISTRY, v.96, no.4, pp.1614 - 1621 | - |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.uri | http://hdl.handle.net/10203/322543 | - |
dc.description.abstract | Metabolite profiling serves as a powerful tool that advances our understanding of biological systems, disease mechanisms, and environmental interactions. In this study, we present an approach employing F-19-nuclear magnetic resonance (F-19 NMR) spectroscopy for plasma amine profiling. This method utilizes a highly efficient and reliable fluorine-labeling reagent, 3,5-difluorosalicylaldehyde, which effectively emulates pyridoxal phosphate, facilitating the formation of Schiff base compounds with primary amines. The fluorine labeling allows for distinct resolution of F-19 NMR signals from amine mixtures, leading to precise identification and quantification of amine metabolites in human plasma. This advancement offers valuable tools for furthering metabolomics research. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Bioinspired Fluorine Labeling for <sup>19</sup>F NMR-Based Plasma Amine Profiling | - |
dc.type | Article | - |
dc.identifier.wosid | 001154863800001 | - |
dc.identifier.scopusid | 2-s2.0-85182982773 | - |
dc.type.rims | ART | - |
dc.citation.volume | 96 | - |
dc.citation.issue | 4 | - |
dc.citation.beginningpage | 1614 | - |
dc.citation.endingpage | 1621 | - |
dc.citation.publicationname | ANALYTICAL CHEMISTRY | - |
dc.identifier.doi | 10.1021/acs.analchem.3c04485 | - |
dc.contributor.localauthor | Kim, Hyunwoo | - |
dc.contributor.nonIdAuthor | Cho, Heyjin | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | METABOLOMICS | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordPlus | PATHWAYS | - |
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