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College of Engineering(공과대학)School of Mechanical and Aerospace Engineering(기계항공공학부)Dept. of Mechanical Engineering(기계공학과)ME-Journal Papers(저널논문)

Nanotherapeutics engineered to cross the blood-brain barrier for advanced drug delivery to the central nervous system

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dc.contributor.authorKim, Jinhwanko
dc.contributor.authorAhn, Song Ihko
dc.contributor.authorKim, YongTaeko
dc.date.accessioned2024-08-06T09:00:15Z-
dc.date.available2024-08-06T09:00:15Z-
dc.date.created2024-08-06-
dc.date.issued2019-05-
dc.identifier.citationJOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.73, pp.8 - 18-
dc.identifier.issn1226-086X-
dc.identifier.urihttp://hdl.handle.net/10203/321745-
dc.description.abstractDrug delivery to the brain remains challenging mainly due to the blood-brain barrier (BBB) that regulates the entrance of substances to the brain. Advances in nanotechnology have enabled the engineering of nanomedicines for biomedical applications including enhanced drug delivery into the brain. In this review, we describe strategies of nanomedicines engineered to traverse the BBB and deliver therapeutic molecules to target brain sites. We highlight the representative applications with materials including polymers, lipids, and inorganic elements for brain drug delivery. We finalize this review with the current challenges and future perspective of nanotherapeutics for advanced drug delivery to the brain. (C) 2019 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE INC-
dc.titleNanotherapeutics engineered to cross the blood-brain barrier for advanced drug delivery to the central nervous system-
dc.typeArticle-
dc.identifier.wosid000462419300002-
dc.identifier.scopusid2-s2.0-85060868116-
dc.type.rimsART-
dc.citation.volume73-
dc.citation.beginningpage8-
dc.citation.endingpage18-
dc.citation.publicationnameJOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY-
dc.identifier.doi10.1016/j.jiec.2019.01.021-
dc.contributor.localauthorAhn, Song Ih-
dc.contributor.nonIdAuthorKim, Jinhwan-
dc.contributor.nonIdAuthorKim, YongTae-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordAuthorNanomedicine-
dc.subject.keywordAuthorDrug delivery-
dc.subject.keywordAuthorBrain disease-
dc.subject.keywordAuthorBlood-brain barrier-
dc.subject.keywordAuthorEngineered nanoparticles-
dc.subject.keywordPlusSOLID LIPID NANOPARTICLES-
dc.subject.keywordPlusTARGETED THERAPY-
dc.subject.keywordPlusGLIOMA THERAPY-
dc.subject.keywordPlusPENETRATING PEPTIDE-
dc.subject.keywordPlusALZHEIMERS-DISEASE-
dc.subject.keywordPlusNANOMEDICINE-
dc.subject.keywordPlusLIPOSOMES-
dc.subject.keywordPlusTUMOR-
dc.subject.keywordPlusGENE-
dc.subject.keywordPlusTRANSFERRIN-
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