DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Kang, Sung-Ho | - |
dc.contributor.advisor | 강성호 | - |
dc.contributor.author | Jung, Byung-Hyuck | - |
dc.contributor.author | 정병혁 | - |
dc.date.accessioned | 2011-12-13T04:49:55Z | - |
dc.date.available | 2011-12-13T04:49:55Z | - |
dc.date.issued | 2004 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=240365&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/31997 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 화학과, 2004.8, [ ii, 43 p. ] | - |
dc.description.abstract | For the synthesis of α-amino-β-hydroxy-γ-butyrolactone 1, the preparation of the key intermediate 16 was considered important. The key feature of the synthetic route to 16 includes azidolysis of trans-epoxide 35 and the regioselective epoxide opening of epoxy alcohol 44 with $NH_4OH$. To develop a stereoselective synthetic pathway to tertiary alcohols, a few experiments were planned. These include: the diastereomeric differentiation of $C_2$ symmetric triol 47 containing 3 or 5 stereogenic centers prepared by one pot-asymmetric allylation/crotylation of di-aldehyde 46 and stepwise asymmetric allylation/crotylation of mono-aldehyde and Lewis acid-catalyzed desymmetrization of meso-triols. Due to the inefficiency in preparing 47, the first approach could not be examined. The second approach has found respective using $C_2-symmetric$ chiral bisoxazolines. | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | SYNTHETIC STUDIES OF Α-AMINO-Β-HYDROXY-Γ-BUTYROLACTONE AND STEREOSELECTIVE SYNTHESES OF TERTIARY ALCOHOLS | - |
dc.subject | 아미노하이드록시 그룹을 갖는 감마 락톤의 합성에 대한 연구와 3차 알코올 입체선택적 형성 반응에 대한 연구 | - |
dc.title | Synthetic studies of α-amino-β-hydroxy-γ-butyrolactone and stereoselective syntheses of tertiary alcohols | - |
dc.title.alternative | 아미노하이드록시 그룹을 갖는 감마 락톤의 합성에 대한 연구와 3차 알코올 입체 선택적 형성 반응에 대한 연구 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 240365/325007 | - |
dc.description.department | 한국과학기술원 : 화학과, | - |
dc.identifier.uid | 020023951 | - |
dc.contributor.localauthor | Kang, Sung-Ho | - |
dc.contributor.localauthor | 강성호 | - |
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