DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Sang Yup | ko |
dc.contributor.author | Kim, Kyung-Jin | ko |
dc.contributor.author | Ahn, Jung Ho | ko |
dc.contributor.author | Seo, Hogyun | ko |
dc.contributor.author | Lee, Jong An | ko |
dc.date.accessioned | 2024-05-24T03:00:34Z | - |
dc.date.available | 2024-05-24T03:00:34Z | - |
dc.identifier.uri | http://hdl.handle.net/10203/319484 | - |
dc.description.abstract | Disclosed are a mutant microorganism for producing succinic acid exhibiting improved activity of conversion of oxaloacetate to malate through the introduction of genes encoding a malate dehydrogenase, wherein an amino acid residue that interacts with a pyrophosphate moiety of NADH through an amide functional group of a main chain of malate dehydrogenase is glutamine (Gln), and a method of producing succinic acid using the same. The mutant microorganism producing succinic acid according to the present invention is capable of producing a high concentration of succinic acid at the highest productivity compared to other mutant microorganisms reported to date when the microorganism is cultured in a limited medium. In addition, the mutant microorganism is capable of producing succinic acid at higher productivity and product concentration through further advanced fermentation technology. | - |
dc.title | Mutant microorganism producing succinic acid using substrate inhibition-relieved malate dehydrogenase and method for preparing succinic acid using the same | - |
dc.title.alternative | 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법 | - |
dc.type | Patent | - |
dc.type.rims | PAT | - |
dc.contributor.localauthor | Lee, Sang Yup | - |
dc.contributor.nonIdAuthor | Kim, Kyung-Jin | - |
dc.contributor.nonIdAuthor | Seo, Hogyun | - |
dc.contributor.assignee | KAIST | - |
dc.identifier.iprsType | 특허 | - |
dc.identifier.patentApplicationNumber | 16490515 | - |
dc.identifier.patentRegistrationNumber | 11655462 | - |
dc.date.application | 2019-05-02 | - |
dc.date.registration | 2023-05-23 | - |
dc.publisher.country | US | - |
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