DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Soo-Hyun | ko |
dc.contributor.author | Bae, Ui-Jin | ko |
dc.contributor.author | Choi, Eun-Kyung | ko |
dc.contributor.author | Jung, Su-Jin | ko |
dc.contributor.author | Lee, Sung-Hyen | ko |
dc.contributor.author | Yang, Jae-Heon | ko |
dc.contributor.author | Kim, You-Suk | ko |
dc.contributor.author | Jeong, Do-Youn | ko |
dc.contributor.author | Kim, Hyun-Ju | ko |
dc.contributor.author | Park, Byung-Hyun | ko |
dc.contributor.author | Chae, Soo-Wan | ko |
dc.date.accessioned | 2024-03-21T08:00:11Z | - |
dc.date.available | 2024-03-21T08:00:11Z | - |
dc.date.created | 2024-03-21 | - |
dc.date.created | 2024-03-21 | - |
dc.date.issued | 2020-07 | - |
dc.identifier.citation | BMC COMPLEMENTARY MEDICINE AND THERAPIES, v.20, no.1 | - |
dc.identifier.issn | 2662-7671 | - |
dc.identifier.uri | http://hdl.handle.net/10203/318606 | - |
dc.description.abstract | Background: Allium hookeriis widely consumed as a vegetable and herbal medicine in Asia.A. hookerihas been reported anti-inflammatory, anti-obesity, osteoblastic, anti-oxidant, and anti-diabetic effects in animal studies. We investigated the anti-diabetic effects ofA. hookeriaqueous extract (AHE) in the Korean subjects. Methods: Prediabetic subjects (100 <= fasting plasma glucose (FPG) < 126 mg/dL) who met the inclusion criteria were recruited for this study. The enrolled subjects (n = 30) were randomly divided into either an AHE (n = 15, 486 mg/day) or placebo (n = 15) group. Outcomes were measurements of FPG, glycemic response to an oral glucose tolerance test (OGTT), insulin, C-peptide, hemoglobin A1c (HbA1c), total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol. Thet-test was used to assess differences between the groups. Ap-value < 0.05 was considered statistically significant. Results: Eight weeks after AHE supplementation, HbA1c level was significantly decreased in the AHE group compared with the placebo group. No clinically significant changes in any safety parameter were observed. Conclusion: The findings suggest that AHE can be effective in reducing HbA1c, indicating it as an adjunctive tool for improving glycemic control. | - |
dc.language | English | - |
dc.publisher | BMC | - |
dc.title | A randomized, double-blind, placebo-controlled crossover clinical trial to evaluate the anti-diabetic effects of Allium hookeri extract in the subjects with prediabetes | - |
dc.type | Article | - |
dc.identifier.wosid | 000550063300003 | - |
dc.identifier.scopusid | 2-s2.0-85094121868 | - |
dc.type.rims | ART | - |
dc.citation.volume | 20 | - |
dc.citation.issue | 1 | - |
dc.citation.publicationname | BMC COMPLEMENTARY MEDICINE AND THERAPIES | - |
dc.identifier.doi | 10.1186/s12906-020-03005-3 | - |
dc.contributor.localauthor | Park, Byung-Hyun | - |
dc.contributor.nonIdAuthor | Park, Soo-Hyun | - |
dc.contributor.nonIdAuthor | Bae, Ui-Jin | - |
dc.contributor.nonIdAuthor | Choi, Eun-Kyung | - |
dc.contributor.nonIdAuthor | Jung, Su-Jin | - |
dc.contributor.nonIdAuthor | Lee, Sung-Hyen | - |
dc.contributor.nonIdAuthor | Yang, Jae-Heon | - |
dc.contributor.nonIdAuthor | Kim, You-Suk | - |
dc.contributor.nonIdAuthor | Jeong, Do-Youn | - |
dc.contributor.nonIdAuthor | Kim, Hyun-Ju | - |
dc.contributor.nonIdAuthor | Chae, Soo-Wan | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Allium hookeri | - |
dc.subject.keywordAuthor | Prediabetes | - |
dc.subject.keywordAuthor | Plasma glucose | - |
dc.subject.keywordAuthor | Oral glucose tolerance test | - |
dc.subject.keywordAuthor | Hemoglobin A1c | - |
dc.subject.keywordAuthor | Incremental area under the curve | - |
dc.subject.keywordPlus | TYPE-2 DIABETES-MELLITUS | - |
dc.subject.keywordPlus | SUPPLEMENTATION | - |
dc.subject.keywordPlus | CYCLOALLIIN | - |
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