DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Dong Oh | ko |
dc.contributor.author | Nam, Hyeong Soo | ko |
dc.contributor.author | Kim, Sunwon | ko |
dc.contributor.author | Yoo, Hongki | ko |
dc.contributor.author | Kim, Jin Won | ko |
dc.date.accessioned | 2023-11-27T02:00:20Z | - |
dc.date.available | 2023-11-27T02:00:20Z | - |
dc.date.created | 2023-11-26 | - |
dc.date.created | 2023-11-26 | - |
dc.date.issued | 2023-08 | - |
dc.identifier.citation | SCIENTIFIC REPORTS, v.13, no.1 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/10203/315206 | - |
dc.description.abstract | <jats:title>Abstract</jats:title><jats:p>Intracoronary optical coherence tomography (OCT) requires injection of flushing media for image acquisition. Alternative flushing media needs to be investigated to reduce the risk of contrast-induced renal dysfunction. We investigated the feasibility and safety of pentastarch (hydroxyethyl starch) for clinical OCT imaging. We prospectively enrolled 43 patients with 70 coronary lesions (46-stented; 24-native). Total 81 OCT pullback pairs were obtained by manual injection of iodine contrast, followed by pentastarch. Each pullback was assessed frame-by-frame using an automated customized lumen contour/stent strut segmentation algorithm. Paired images were compared for the clear image segments (CIS), blood-flushing capability, and quantitative morphometric measurements. Overall image quality, as assessed by the proportion of CIS, was comparable between the contrast- and pentastarch-flushed images (97.1% vs. 96.5%; p = 0.160). The pixel-based blood-flushing capability was similar between the groups (0.951 [0.947–0.953] vs. 0.950 [0.948–0.952], p = 0.125). Quantitative two- and three-dimensional morphometric measurements of the paired images correlated well (p &lt; 0.001) with excellent inter-measurement variability. All patients safely underwent OCT imaging using pentastarch without resulting in clinically relevant complications or renal deterioration. Non-contrast OCT imaging using pentastarch is clinically safe and technically feasible with excellent image quality and could be a promising alternative strategy for patients at high risk of renal impairment.</jats:p> | - |
dc.language | English | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Feasibility and safety of non-contrast optical coherence tomography imaging using hydroxyethyl starch in coronary arteries | - |
dc.type | Article | - |
dc.identifier.wosid | 001113423900019 | - |
dc.identifier.scopusid | 2-s2.0-85168677498 | - |
dc.type.rims | ART | - |
dc.citation.volume | 13 | - |
dc.citation.issue | 1 | - |
dc.citation.publicationname | SCIENTIFIC REPORTS | - |
dc.identifier.doi | 10.1038/s41598-023-40363-7 | - |
dc.contributor.localauthor | Yoo, Hongki | - |
dc.contributor.nonIdAuthor | Kang, Dong Oh | - |
dc.contributor.nonIdAuthor | Kim, Sunwon | - |
dc.contributor.nonIdAuthor | Kim, Jin Won | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | MOLECULAR-WEIGHT DEXTRAN | - |
dc.subject.keywordPlus | INDUCED NEPHROPATHY | - |
dc.subject.keywordPlus | AMERICAN-COLLEGE | - |
dc.subject.keywordPlus | RESUSCITATION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | FREQUENCY | - |
dc.subject.keywordPlus | SALINE | - |
dc.subject.keywordPlus | MEDIA | - |
dc.subject.keywordPlus | INTERVENTION | - |
dc.subject.keywordPlus | GUIDELINES | - |
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