Dynamic switching of neural oscillations in the prefrontal-amygdala circuit for naturalistic freeze-or-flight

Cited 1 time in webofscience Cited 0 time in scopus
  • Hit : 75
  • Download : 0
DC FieldValueLanguage
dc.contributor.authorHan, Hio-Beenko
dc.contributor.authorShin, Hee-Supko
dc.contributor.authorJeong, Yongko
dc.contributor.authorKim, Jisooko
dc.contributor.authorChoi, Jee Hyunko
dc.date.accessioned2023-11-13T07:00:20Z-
dc.date.available2023-11-13T07:00:20Z-
dc.date.created2023-11-13-
dc.date.created2023-11-13-
dc.date.issued2023-09-
dc.identifier.citationPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.120, no.37-
dc.identifier.issn0027-8424-
dc.identifier.urihttp://hdl.handle.net/10203/314522-
dc.description.abstractThe medial prefrontal cortex (mPFC) and basolateral amygdala (BLA) are involved in the regulation of defensive behavior under threat, but their engagement in flexible behavior shifts remains unclear. Here, we report the oscillatory activities of mPFC–BLA circuit in reaction to a naturalistic threat, created by a predatory robot in mice. Specifically, we found dynamic frequency tuning among two different theta rhythms (~5 or ~10 Hz) was accompanied by agile changes of two different defensive behaviors (freeze-or-flight). By analyzing flight trajectories, we also found that high beta (~30 Hz) is engaged in the top–down process for goal-directed flights and accompanied by a reduction in fast gamma (60 to 120 Hz, peak near 70 Hz). The elevated beta nested the fast gamma activity by its phase more strongly. Our results suggest that the mPFC–BLA circuit has a potential role in oscillatory gear shifting allowing flexible information routing for behavior switches.-
dc.languageEnglish-
dc.publisherNATL ACAD SCIENCES-
dc.titleDynamic switching of neural oscillations in the prefrontal-amygdala circuit for naturalistic freeze-or-flight-
dc.typeArticle-
dc.identifier.wosid001119304600003-
dc.identifier.scopusid2-s2.0-85169757979-
dc.type.rimsART-
dc.citation.volume120-
dc.citation.issue37-
dc.citation.publicationnamePROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-
dc.identifier.doi10.1073/pnas.2308762120-
dc.contributor.localauthorJeong, Yong-
dc.contributor.nonIdAuthorShin, Hee-Sup-
dc.contributor.nonIdAuthorKim, Jisoo-
dc.contributor.nonIdAuthorChoi, Jee Hyun-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorneural synchrony-
dc.subject.keywordAuthorbehavioral switching-
dc.subject.keywordAuthordefensive behaviors-
dc.subject.keywordAuthortheta oscillations-
dc.subject.keywordAuthorbeta oscillations-
dc.subject.keywordPlusNEURONAL CIRCUITS-
dc.subject.keywordPlusFEAR-
dc.subject.keywordPlusFREQUENCY-
dc.subject.keywordPlusSYNCHRONIZATION-
dc.subject.keywordPlusCOMMUNICATION-
dc.subject.keywordPlusINFORMATION-
dc.subject.keywordPlusMOVEMENT-
dc.subject.keywordPlusBEHAVIOR-
dc.subject.keywordPlusRHYTHMS-
dc.subject.keywordPlusCORTEX-
Appears in Collection
BiS-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 1 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0