DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Seoyoung | ko |
dc.contributor.author | Kim, Juyeong | ko |
dc.contributor.author | Kang, Kyungjun | ko |
dc.contributor.author | Lee, Ansoo | ko |
dc.contributor.author | Kim, Hyunwoo | ko |
dc.date.accessioned | 2023-08-24T03:00:21Z | - |
dc.date.available | 2023-08-24T03:00:21Z | - |
dc.date.created | 2023-08-14 | - |
dc.date.issued | 2023-08 | - |
dc.identifier.citation | ADVANCED SYNTHESIS & CATALYSIS, v.365, no.15, pp.2615 - 2621 | - |
dc.identifier.issn | 1615-4150 | - |
dc.identifier.uri | http://hdl.handle.net/10203/311771 | - |
dc.description.abstract | In this study, we focused on the synthesis of tetraazamacrocycles, an essential class of macrocyclic compounds with applications in coordination chemistry, pharmaceuticals, and catalysis. To accomplish this, we developed a ligand-controlled palladium-catalyzed allylic substitution approach using bicyclic bridgehead phosphoramidite (briphos) ligands. This approach allowed us to selectively achieve [1+1] and [1+2] allylic aminations between allylic diols and diamines, while avoiding the formation of cyclic [1+1] products. By combining this approach with sequential acetylation and allylic amination, we successfully synthesized tetraazamacrocycles with ring sizes ranging from 16 to 38. These findings demonstrate the potential of a sequential allylation strategy for synthesizing complex molecules with broad applications in the fields of chemistry, pharmaceuticals, and medicine. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Synthesis of Tetraazamacrocycles by Sequential Palladium-Catalyzed Allylic Substitution Reactions | - |
dc.type | Article | - |
dc.identifier.wosid | 001037276000001 | - |
dc.identifier.scopusid | 2-s2.0-85165948499 | - |
dc.type.rims | ART | - |
dc.citation.volume | 365 | - |
dc.citation.issue | 15 | - |
dc.citation.beginningpage | 2615 | - |
dc.citation.endingpage | 2621 | - |
dc.citation.publicationname | ADVANCED SYNTHESIS & CATALYSIS | - |
dc.identifier.doi | 10.1002/adsc.202300469 | - |
dc.contributor.localauthor | Kim, Hyunwoo | - |
dc.contributor.nonIdAuthor | Lee, Seoyoung | - |
dc.contributor.nonIdAuthor | Kim, Juyeong | - |
dc.contributor.nonIdAuthor | Lee, Ansoo | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Tetraazamacrocycles | - |
dc.subject.keywordAuthor | Allylic substitution | - |
dc.subject.keywordAuthor | Phosphorus ligands | - |
dc.subject.keywordAuthor | Homogeneous catalysis | - |
dc.subject.keywordAuthor | Palladium catalyst | - |
dc.subject.keywordPlus | TANDEM ALLYLATION | - |
dc.subject.keywordPlus | CYCLEN | - |
dc.subject.keywordPlus | CYCLIZATION | - |
dc.subject.keywordPlus | TRANSITION | - |
dc.subject.keywordPlus | ALCOHOLS | - |
dc.subject.keywordPlus | LIGANDS | - |
dc.subject.keywordPlus | AMINES | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.