In the EPCglobal standards for RFID architecture frameworks and interfaces, the Electronic Product Code Information System (EPCIS) acts as a standard repository storing event and master data that are well suited to Supply Chain Management (SCM) applications. Oliot-EPCIS broadens its scope to a wider range of IoT applications in a scalable and flexible way to store a large amount of heterogeneous data from a variety of sources. However, this expansion poses data security challenge for IoT applications including patients' ownership of events generated in mobile healthcare services. Thus, in this paper we propose Secure-EPCIS to deal with security issues of EPCIS for IoT applications. We have analyzed the requirements for Secure-EPCIS based on real-world scenarios and designed access control model accordingly. Moreover, we have conducted extensive performance comparisons between EPCIS and Secure-EPCIS in terms of response time and throughput, and provide the solution for performance degradation problem in Secure-EPCIS.