DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Chungha | ko |
dc.contributor.author | Hugonnet, Herve | ko |
dc.contributor.author | Park, Juyeon | ko |
dc.contributor.author | Lee, Mahn Jae | ko |
dc.contributor.author | Park, Weisun | ko |
dc.contributor.author | Park, Yongkeun | ko |
dc.date.accessioned | 2023-06-21T03:01:09Z | - |
dc.date.available | 2023-06-21T03:01:09Z | - |
dc.date.created | 2023-06-21 | - |
dc.date.created | 2023-06-21 | - |
dc.date.issued | 2023-04 | - |
dc.identifier.citation | OPTICS EXPRESS, v.31, no.9, pp.13806 - 13816 | - |
dc.identifier.issn | 1094-4087 | - |
dc.identifier.uri | http://hdl.handle.net/10203/307381 | - |
dc.description.abstract | The refractive index (RI) of cells and tissues is crucial in pathophysiology as a noninvasive and quantitative imaging contrast. Although its measurements have been demon-strated using three-dimensional quantitative phase imaging methods, these methods often require bulky interferometric setups or multiple measurements, which limits the measurement sensitivity and speed. Here, we present a single-shot RI imaging method that visualizes the RI of the in-focus region of a sample. By exploiting spectral multiplexing and optical transfer function engineering, three color-coded intensity images of a sample with three optimized illuminations were simultaneously obtained in a single-shot measurement. The measured intensity images were then deconvoluted to obtain the RI image of the in-focus slice of the sample. As a proof of concept, a setup was built using Fresnel lenses and a liquid-crystal display. For validation purposes, we measured microspheres of known RI and cross-validated the results with simulated results. Various static and highly dynamic biological cells were imaged to demonstrate that the proposed method can conduct single-shot RI slice imaging of biological samples with subcellular resolution. | - |
dc.language | English | - |
dc.publisher | Optica Publishing Group | - |
dc.title | Single-shot refractive index slice imaging using spectrally multiplexed optical transfer function reshaping | - |
dc.type | Article | - |
dc.identifier.wosid | 000988193100002 | - |
dc.identifier.scopusid | 2-s2.0-85158016337 | - |
dc.type.rims | ART | - |
dc.citation.volume | 31 | - |
dc.citation.issue | 9 | - |
dc.citation.beginningpage | 13806 | - |
dc.citation.endingpage | 13816 | - |
dc.citation.publicationname | OPTICS EXPRESS | - |
dc.identifier.doi | 10.1364/OE.485559 | - |
dc.contributor.localauthor | Park, Yongkeun | - |
dc.contributor.nonIdAuthor | Lee, Mahn Jae | - |
dc.contributor.nonIdAuthor | Park, Weisun | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | DIFFRACTION TOMOGRAPHY | - |
dc.subject.keywordPlus | CONTRAST | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | QUANTIFICATION | - |
dc.subject.keywordPlus | ILLUMINATION | - |
dc.subject.keywordPlus | RESOLUTION | - |
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