A fluorescent hydrazone exchange probe of pyridoxal phosphate for the assessment of vitamin B6 status
Abnormal vitamin B6 status, marked by deficient intracellular concentrations of pyridoxal phosphate (PLP), is classified as a direct biomarker based on its biomedical significance. However, there exist no direct methods for measuring vitamin B6 status in intact cells. Here we describe the development of a fluorogenic probe, RAB6, which shows remarkable selectivity for PLP among the B6 vitamers and other cellular aldehydes.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2020-01
- Language
- English
- Article Type
- Article
- Citation
CHEMICAL COMMUNICATIONS, v.56, no.2, pp.317 - 320
- ISSN
- 1359-7345
- Appears in Collection
- CH-Journal Papers(저널논문)
- Files in This Item
- There are no files associated with this item.
This item is cited by other documents in WoS
| ⊙ Detail Information in WoSⓡ | Click to see |  |
| ⊙ Cited 11 items in WoS | Click to see citing articles in |  |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.