Method and apparatus for statistically multiplexing corresponding channels using an orthogonal code hopping in a wire/wireless communication system in which a plurality of synchronized communication channels coexist through one media. The system including a first communication station and a plurality of second communications includes an orthogonal code hopping pattern generator, a spreader for selecting a corresponding orthogonal code symbol in the orthogonal code, a collision comparator and controller for monitoring whether the orthogonal code symbols collide and determing whether the sent data symbols to the second communication stations coincide in the collision area, a unit for stopping transmission in case of collision of the hopping patterns and discordance of the transmission data symbols, and a transmission power controller for compensating an average receiving energy loss.